VPS53 and EXOC2

Number of citations of the paper that reports this interaction (PMID 20685960)
14

Data Source:
BioGRID (two hybrid)

		VPS53	EXOC2
Gene Name		vacuolar protein sorting 53 homolog (S. cerevisiae)	exocyst complex component 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	GARP Complex Golgi Apparatus Endosome Membrane Perinuclear Region Of Cytoplasm	Exocyst Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding Ral GTPase Binding Protein Kinase Binding Protein N-terminus Binding
	Biological Process	Protein Transport Retrograde Transport, Endosome To Golgi	Exocytosis Golgi To Plasma Membrane Transport Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization
Pathways			Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Basal cell carcinoma ( 21700618) Black vs. blond hair color ( 18483556) Black vs. red hair color ( 18483556) Dental caries ( 23064961) Non-melanoma skin cancer ( 23548203) Schizophrenia ( 22885689) Tanning ( 19340012)
Protein-Protein Interactions		4 interactors: EXOC2 VPS51 VPS52 VPS54	7 interactors: ESX1 EXOC3 EXOC7 EXOC8 RALA SERGEF VPS53
Entrez ID		55275	55770
HPRD ID		07720	11544
Ensembl ID		ENSG00000141252	ENSG00000112685
Uniprot IDs		B3KS06 Q5VIR6	B2RBE6 Q96KP1
PDB IDs
Enriched GO Terms of Interacting Partners?		Post-Golgi Vesicle-mediated Transport Golgi Vesicle Transport Golgi To Plasma Membrane Transport Protein Transport Establishment Of Protein Localization Protein Localization Retrograde Transport, Endosome To Golgi Cytoplasmic Transport Embryonic Ectodermal Digestive Tract Development Endosomal Transport Vesicle-mediated Transport Ectodermal Cell Differentiation Intracellular Transport Golgi To Vacuole Transport Transport Establishment Of Localization In Cell Neurofilament Cytoskeleton Organization Cellular Localization Ectoderm Development Homeostasis Of Number Of Cells Within A Tissue Intermediate Filament Cytoskeleton Organization Embryonic Digestive Tract Development Intermediate Filament-based Process Musculoskeletal Movement Vacuolar Transport Digestive Tract Development Digestive System Development	Exocyst Localization Exocytosis Secretion By Cell Cellular Protein Complex Localization Protein Complex Localization Vesicle-mediated Transport Secretion Membrane Organization Establishment Of Localization In Cell Cellular Localization Exocyst Assembly Protein Transport Establishment Of Protein Localization Membrane Raft Localization Protein Localization Positive Regulation Of Ran GTPase Activity Transport Labyrinthine Layer Morphogenesis
Tagcloud ?		biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps52 vps54 wobbler	agouti albinism asip atf1 delta25 dopachrome edn1 edn3 ednrb exocyst kitlg ludwigshafen mc1r microphthalmia oca2 oculocutaneous pigmentation prkacb prkacg prkar1a prkar2a prkar2b proopiomelanocortin slc24a4 slc45a2 tautomerase tpcn2 tubb3 tyrp1
Tagcloud (Difference) ?		biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps52 vps54 wobbler	agouti albinism asip atf1 delta25 dopachrome edn1 edn3 ednrb exocyst kitlg ludwigshafen mc1r microphthalmia oca2 oculocutaneous pigmentation prkacb prkacg prkar1a prkar2a prkar2b proopiomelanocortin slc24a4 slc45a2 tautomerase tpcn2 tubb3 tyrp1
Tagcloud (Intersection) ?