UMPS and CALU

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		UMPS	CALU
Gene Name		uridine monophosphate synthetase	calumenin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Extracellular Region Endoplasmic Reticulum Golgi Apparatus Membrane Sarcoplasmic Reticulum Lumen Melanosome
	Molecular Function	Orotate Phosphoribosyltransferase Activity Orotidine-5'-phosphate Decarboxylase Activity	Calcium Ion Binding Protein Binding
	Biological Process	Pyrimidine Nucleobase Metabolic Process 'de Novo' Pyrimidine Nucleobase Biosynthetic Process UMP Biosynthetic Process Female Pregnancy Lactation Cellular Response To Drug 'de Novo' UMP Biosynthetic Process Small Molecule Metabolic Process Pyrimidine Nucleoside Biosynthetic Process Nucleobase-containing Small Molecule Metabolic Process	Platelet Degranulation Blood Coagulation Biological_process Platelet Activation
Pathways		Pyrimidine biosynthesis Pyrimidine metabolism Metabolism of nucleotides	Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS			Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328)
Protein-Protein Interactions		10 interactors: A2M CALU CDC42EP3 DLST NOS3 PAXIP1 PLA2G12A PSEN1 RPS29 ZNF227	7 interactors: APCS CSNK2A1 CTNNAL1 PRMT5 UBQLN1 UMPS ZPBP
Entrez ID		7372	813
HPRD ID		02022	04569
Ensembl ID
Uniprot IDs		A8K5J1 B5LY70 P11172	B3KQF5 O43852 Q6IAW5
PDB IDs		2EAW 2JGY 2P1F 2QCC 2QCD 2QCE 2QCF 2QCG 2QCH 2QCL 2QCM 2QCN 2V30 2WNS 3BGG 3BGJ 3BK0 3BVJ 3DBP 3EWU 3EWW 3EWX 3EWY 3EWZ 3EX1 3EX2 3EX3 3EX4 3EX6 3G3D 3G3M 3L0K 3L0N 3MI2 3MO7 3MW7 4HIB 4HKP
Enriched GO Terms of Interacting Partners?		Exocytosis Platelet Degranulation Cajal-Retzius Cell Differentiation Positive Regulation Of Histone H3-K36 Methylation Beta-amyloid Formation Catabolic Process Endothelial Cell Migration Intracellular Signal Transduction Blood Coagulation Hemostasis Extracellular Matrix Disassembly Epithelial Cell Migration Epithelium Migration Smooth Muscle Hyperplasia Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Complement Activation, Lectin Pathway Secretion By Cell Blood Vessel Development Cellular Amino Acid Catabolic Process Vasculature Development Cellular Nitrogen Compound Metabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Regulation Of Body Fluid Levels Smooth Muscle Adaptation Synaptic Vesicle Targeting Regulation Of Resting Membrane Potential Wound Healing Secretion Negative Regulation Of Muscle Hyperplasia Regulation Of Systemic Arterial Blood Pressure By Endothelin Nitrogen Compound Metabolic Process Positive Regulation Of Protein Complex Assembly Cell Activation Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Choline Transport Ameboidal-type Cell Migration Response To Wounding Platelet Activation Regulation Of Protein Ubiquitination Carboxylic Acid Catabolic Process Regulation Of The Force Of Heart Contraction By Chemical Signal Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Catalytic Activity Lysine Catabolic Process Arginine Catabolic Process Chorion Development Amyloid Precursor Protein Catabolic Process Negative Regulation Of Cellular Protein Metabolic Process Cell Migration Positive Regulation Of Guanylate Cyclase Activity	Regulation Of Mitotic Nuclear Division Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Negative Regulation Of Exo-alpha-sialidase Activity 'de Novo' UMP Biosynthetic Process Negative Regulation Of Monocyte Differentiation Regulation Of Cell Division 'de Novo' Pyrimidine Nucleobase Biosynthetic Process Protein Folding Rhythmic Process Histone H4-R3 Methylation Negative Regulation Of Glycoprotein Metabolic Process Endothelial Cell Activation UMP Biosynthetic Process Chaperone-mediated Protein Complex Assembly Regulation Of Monocyte Differentiation Negative Regulation Of Acute Inflammatory Response Acrosome Assembly Negative Regulation Of Viral Entry Into Host Cell Peptidyl-arginine N-methylation Negative Regulation Of Hydrolase Activity Regulation Of Mitotic Cell Cycle Histone Arginine Methylation Regulation Of Viral Entry Into Host Cell Peptidyl-arginine Methylation Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Tagcloud ?		acrofacial arch auxotrophic biallelic biosynthesis bud cad complementation dho dhodehase dhodh dihydroorotate discrepancies discrepant dysostosis exceptional genee miller mim missense novo oa orotic pharyngeal postaxial predicts pyrimidine requirement weidemann	abrogate abrogates atf coactivators coexpression correlate creb exert g1 g148v hela htlv immortalization interfere lymphotropic m22 m47 oligonucleotide overexpressing p53 prevents rel suppress suppression tat tax transactivation transactivator transforms
Tagcloud (Difference) ?		acrofacial arch auxotrophic biallelic biosynthesis bud cad complementation dho dhodehase dhodh dihydroorotate discrepancies discrepant dysostosis exceptional genee miller mim missense novo oa orotic pharyngeal postaxial predicts pyrimidine requirement weidemann	abrogate abrogates atf coactivators coexpression correlate creb exert g1 g148v hela htlv immortalization interfere lymphotropic m22 m47 oligonucleotide overexpressing p53 prevents rel suppress suppression tat tax transactivation transactivator transforms
Tagcloud (Intersection) ?