UMPS and RPS29

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		UMPS	RPS29
Gene Name		uridine monophosphate synthetase	ribosomal protein S29
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Cytoplasm Cytosol Focal Adhesion Small Ribosomal Subunit Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Orotate Phosphoribosyltransferase Activity Orotidine-5'-phosphate Decarboxylase Activity	Structural Constituent Of Ribosome Zinc Ion Binding
	Biological Process	Pyrimidine Nucleobase Metabolic Process 'de Novo' Pyrimidine Nucleobase Biosynthetic Process UMP Biosynthetic Process Female Pregnancy Lactation Cellular Response To Drug 'de Novo' UMP Biosynthetic Process Small Molecule Metabolic Process Pyrimidine Nucleoside Biosynthetic Process Nucleobase-containing Small Molecule Metabolic Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Pyrimidine biosynthesis Pyrimidine metabolism Metabolism of nucleotides	Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Post-traumatic stress disorder (asjusted for relatedness) ( 23726511) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Visceral fat ( 22589738)
Protein-Protein Interactions		10 interactors: A2M CALU CDC42EP3 DLST NOS3 PAXIP1 PLA2G12A PSEN1 RPS29 ZNF227	4 interactors: ADH6 CTBP2 SMARCD1 UMPS
Entrez ID		7372	6235
HPRD ID		02022	04698
Ensembl ID			ENSG00000213741
Uniprot IDs		A8K5J1 B5LY70 P11172	P62273
PDB IDs		2EAW 2JGY 2P1F 2QCC 2QCD 2QCE 2QCF 2QCG 2QCH 2QCL 2QCM 2QCN 2V30 2WNS 3BGG 3BGJ 3BK0 3BVJ 3DBP 3EWU 3EWW 3EWX 3EWY 3EWZ 3EX1 3EX2 3EX3 3EX4 3EX6 3G3D 3G3M 3L0K 3L0N 3MI2 3MO7 3MW7 4HIB 4HKP	2ZKQ 3J3A
Enriched GO Terms of Interacting Partners?		Exocytosis Platelet Degranulation Cajal-Retzius Cell Differentiation Positive Regulation Of Histone H3-K36 Methylation Beta-amyloid Formation Catabolic Process Endothelial Cell Migration Intracellular Signal Transduction Blood Coagulation Hemostasis Extracellular Matrix Disassembly Epithelial Cell Migration Epithelium Migration Smooth Muscle Hyperplasia Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Complement Activation, Lectin Pathway Secretion By Cell Blood Vessel Development Cellular Amino Acid Catabolic Process Vasculature Development Cellular Nitrogen Compound Metabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Regulation Of Body Fluid Levels Smooth Muscle Adaptation Synaptic Vesicle Targeting Regulation Of Resting Membrane Potential Wound Healing Secretion Negative Regulation Of Muscle Hyperplasia Regulation Of Systemic Arterial Blood Pressure By Endothelin Nitrogen Compound Metabolic Process Positive Regulation Of Protein Complex Assembly Cell Activation Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Choline Transport Ameboidal-type Cell Migration Response To Wounding Platelet Activation Regulation Of Protein Ubiquitination Carboxylic Acid Catabolic Process Regulation Of The Force Of Heart Contraction By Chemical Signal Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Catalytic Activity Lysine Catabolic Process Arginine Catabolic Process Chorion Development Amyloid Precursor Protein Catabolic Process Negative Regulation Of Cellular Protein Metabolic Process Cell Migration Positive Regulation Of Guanylate Cyclase Activity	'de Novo' UMP Biosynthetic Process Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Chromatin Binding 'de Novo' Pyrimidine Nucleobase Biosynthetic Process Chromatin-mediated Maintenance Of Transcription UMP Biosynthetic Process Ethanol Oxidation Nucleosome Disassembly White Fat Cell Differentiation Positive Regulation Of Gene Expression, Epigenetic Viral Genome Replication Pyrimidine Nucleobase Metabolic Process
Tagcloud ?		acrofacial arch auxotrophic biallelic biosynthesis bud cad complementation dho dhodehase dhodh dihydroorotate discrepancies discrepant dysostosis exceptional genee miller mim missense novo oa orotic pharyngeal postaxial predicts pyrimidine requirement weidemann	26s a2 carcinogenesis consistently cytochromosome detecting differentially dot dysplasia est etc expressions ferritin fragments gastric hybridization hypothetical mucosa oxidase proteasome rps12 screen semi ssh stages subtractive tags transcriptase verifying
Tagcloud (Difference) ?		acrofacial arch auxotrophic biallelic biosynthesis bud cad complementation dho dhodehase dhodh dihydroorotate discrepancies discrepant dysostosis exceptional genee miller mim missense novo oa orotic pharyngeal postaxial predicts pyrimidine requirement weidemann	26s a2 carcinogenesis consistently cytochromosome detecting differentially dot dysplasia est etc expressions ferritin fragments gastric hybridization hypothetical mucosa oxidase proteasome rps12 screen semi ssh stages subtractive tags transcriptase verifying
Tagcloud (Intersection) ?