CD3EAP and TAF1A

Number of citations of the paper that reports this interaction (PMID 15226435)
10

Data Source:
HPRD (in vivo, in vitro)

		CD3EAP	TAF1A
Gene Name		CD3e molecule, epsilon associated protein	TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	RNA Polymerase I Transcription Factor Complex Nucleus Nucleoplasm Chromosome Nucleolus DNA-directed RNA Polymerase I Complex Cytoplasm Mitochondrion	RNA Polymerase I Transcription Factor Complex Nucleus Nucleoplasm Microtubule Cytoskeleton Intracellular Membrane-bounded Organelle
	Molecular Function	DNA-directed RNA Polymerase Activity Poly(A) RNA Binding	DNA Binding Protein Binding
	Biological Process	Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway RRNA Transcription Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic	Chromatin Silencing At RDNA Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression	NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression SIRT1 negatively regulates rRNA Expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CD3E NCL NFKBIB POLR1C POLR1D POLR1E TAF1A UBTF	21 interactors: ANP32A C11orf57 CD3EAP ESR1 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE HIST3H3 HIST4H4 JMJD6 RRN3 RUNX2 SET TAF12 TAF1B TAF1C TAF1D TBP TP53 UBTF
Entrez ID		10849	9015
HPRD ID		00125	05362
Ensembl ID		ENSG00000117877	ENSG00000143498
Uniprot IDs		O15446	A8K4K5 B4DS21 Q15573
PDB IDs
Enriched GO Terms of Interacting Partners?		Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic DNA-templated Transcription, Elongation Regulation Of Gene Expression, Epigenetic DNA-templated Transcription, Initiation Positive Regulation Of Type I Interferon Production Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Regulation Of Type I Interferon Production Positive Regulation Of Cytokine Production Regulation Of Cytokine Production Transcription From RNA Polymerase III Promoter Positive Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Transcription From RNA Polymerase I Promoter Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Innate Immune Response Regulation Of Metabolic Process Regulation Of Gene Expression RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Immune System Process Macromolecule Biosynthetic Process Immune Response Defense Response Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of T Cell Anergy Nitrogen Compound Metabolic Process Regulation Of T Cell Anergy Positive Regulation Of T Cell Tolerance Induction Negative Thymic T Cell Selection Signal Complex Assembly Positive Regulation Of Alpha-beta T Cell Proliferation Positive Regulation Of Interleukin-2 Biosynthetic Process Negative T Cell Selection Chromatin Silencing At RDNA Thymic T Cell Selection	Chromatin Silencing At RDNA Negative Regulation Of Gene Expression, Epigenetic Transcription Initiation From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter Chromatin Silencing DNA-templated Transcription, Initiation Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Regulation Of Gene Expression, Epigenetic DNA-templated Transcription, Elongation Gene Silencing Negative Regulation Of Gene Expression Gene Expression Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Termination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Organization Cellular Nitrogen Compound Metabolic Process Chromosome Organization Nitrogen Compound Metabolic Process Chromatin Assembly Regulation Of Gene Expression Chromatin Assembly Or Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Protein-DNA Complex Assembly RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Packaging Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Nucleosome Assembly Cellular Macromolecule Biosynthetic Process DNA Replication-dependent Nucleosome Assembly Macromolecule Biosynthetic Process DNA Conformation Change Nucleosome Organization RNA Metabolic Process DNA Methylation On Cytosine RRNA Transcription Regulation Of Metabolic Process Organelle Organization Biosynthetic Process Negative Regulation Of Cellular Metabolic Process
Tagcloud ?			analysed blocking c8 coding crc frameshift gc harboured heterogeneity instability intratumoural ith microsatellite mononucleotide msi mss mutational regional ribosomal rrna somatic strand summary taf1b taf1c tata tbp tumourigenesis ubf
Tagcloud (Difference) ?			analysed blocking c8 coding crc frameshift gc harboured heterogeneity instability intratumoural ith microsatellite mononucleotide msi mss mutational regional ribosomal rrna somatic strand summary taf1b taf1c tata tbp tumourigenesis ubf
Tagcloud (Intersection) ?