POLR1G and TAF1A

Number of citations of the paper that reports this interaction (PubMedID 15226435)
57

Data Source:
HPRD (in vivo, in vitro)

		POLR1G	TAF1A
Description		RNA polymerase I subunit G	TATA-box binding protein associated factor, RNA polymerase I subunit A
Image			No pdb structure
GO Annotations	Cellular Component	RNA Polymerase I Transcription Regulator Complex DNA-directed RNA Polymerase Complex Fibrillar Center Nucleus Nucleoplasm Chromosome Nucleolus RNA Polymerase I Complex Mitochondrion Cytosol	RNA Polymerase I Transcription Regulator Complex Nucleus Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus Microtubule Cytoskeleton
	Molecular Function	RNA Binding Protein Binding	DNA Binding Protein Binding
	Biological Process	Transcription By RNA Polymerase I Transcription Initiation At RNA Polymerase I Promoter Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway RRNA Transcription	Transcription By RNA Polymerase I Transcription By RNA Polymerase II
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS			Trunk fat mass ( 28552196)
Interacting Genes		6 interacting genes: CD3E NFKBIB POLR1C POLR1E TAF1A UBTF	20 interacting genes: ANP32A ESR1 H2AC20 H2BC21 H3-4 H3C1 H4C1 H4C16 JMJD6 NKAPD1 POLR1G RRN3 RUNX2 SET TAF12 TAF1B TAF1C TBP TP53 UBTF
Entrez ID		10849	9015
HPRD ID		00125	05362
Ensembl ID		ENSG00000117877	ENSG00000143498
Uniprot IDs		O15446	A8K4K5 B4DS21 Q15573
PDB IDs		7OB9 7OBA 7OBB 7VBA 7VBB 7VBC 8A43
Enriched GO Terms of Interacting Partners?		Transcription By RNA Polymerase I DNA-templated Transcription Transcription Initiation At RNA Polymerase I Promoter Nucleobase-containing Compound Biosynthetic Process RNA Polymerase I Preinitiation Complex Assembly RNA Polymerase I Complex Fibrillar Center RNA Metabolic Process Macromolecule Biosynthetic Process DNA-directed RNA Polymerase Complex Nucleolus Transcription Preinitiation Complex Assembly Nucleic Acid Metabolic Process DNA-templated Transcription Initiation RNA Polymerase I General Transcription Initiation Factor Binding Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Maintenance Of Protein Location In Plasma Membrane RNA Polymerase I Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Cell Communication By Electrical Coupling Gamma-delta T Cell Receptor Complex Nucleobase-containing Compound Metabolic Process RNA Polymerase I Transcription Regulator Complex T Cell Anergy Regulation Of Glucose Mediated Signaling Pathway Nucleolar Large RRNA Transcription By RNA Polymerase I Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential RNA Polymerase I General Transcription Initiation Factor Activity RNA Polymerase Transcription Factor SL1 Complex Cellular Response To Magnesium Ion Positive Regulation Of T Cell Anergy Positive Regulation Of Cell-cell Adhesion Mediated By Integrin T Cell Tolerance Induction Protein-DNA Complex Assembly Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Spectrin-associated Cytoskeleton Channel Activator Activity Regulation Of Membrane Depolarization During Action Potential Negative Regulation Of Voltage-gated Potassium Channel Activity Negative Regulation Of Delayed Rectifier Potassium Channel Activity Alpha-beta T Cell Receptor Complex Signal Complex Assembly Regulation Of T Cell Anergy Transcription Elongation By RNA Polymerase I Regulation Of Delayed Rectifier Potassium Channel Activity CD4-positive, Alpha-beta T Cell Proliferation RNA Polymerase I Core Promoter Sequence-specific DNA Binding Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of T Cell Tolerance Induction Positive Regulation Of Membrane Potential Protein Localization To Axon	Protein-DNA Complex Assembly Protein-containing Complex Assembly RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Transcription Preinitiation Complex Assembly Protein-containing Complex Organization Transcription Initiation At RNA Polymerase I Promoter DNA Binding DNA-templated Transcription Initiation Nucleoplasm Structural Constituent Of Chromatin Chromatin Remodeling Cellular Component Assembly Nucleosome Assembly Protein Heterodimerization Activity Transcription By RNA Polymerase I Nucleosome Nucleosome Organization Chromatin Organization DNA-templated Transcription RNA Polymerase Transcription Factor SL1 Complex RNA Polymerase I General Transcription Initiation Factor Activity Nucleus Macromolecule Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process RNA Metabolic Process Regulation Of DNA-templated Transcription Initiation RRNA Transcription TBP-class Protein Binding Nucleic Acid Metabolic Process RNA Polymerase I Transcription Regulator Complex TFIIB-class Transcription Factor Binding Chromosome Fibroblast Proliferation Protein-containing Complex RNA Polymerase II Preinitiation Complex Assembly Protein Localization To Chromatin Nucleobase-containing Compound Metabolic Process MRNA Transcription Positive Regulation Of Transcription Initiation By RNA Polymerase II Nucleolus Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Chromatin Binding Core Promoter Sequence-specific DNA Binding CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Protein Localization To Chromosome Stem Cell Differentiation
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