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POLR1G and NFKBIB
Number of citations of the paper that reports this interaction (PubMedID
14743216
)
0
Data Source:
HPRD
(in vitro)
POLR1G
NFKBIB
Description
RNA polymerase I subunit G
NFKB inhibitor beta
Image
GO Annotations
Cellular Component
RNA Polymerase I Transcription Regulator Complex
DNA-directed RNA Polymerase Complex
Fibrillar Center
Nucleus
Nucleoplasm
Chromosome
Nucleolus
RNA Polymerase I Complex
Mitochondrion
Cytosol
Nucleus
Cytoplasm
Cytosol
Molecular Function
RNA Binding
Protein Binding
Transcription Coactivator Activity
Protein Binding
Biological Process
Transcription By RNA Polymerase I
Transcription Initiation At RNA Polymerase I Promoter
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
RRNA Transcription
DNA-templated Transcription
Inflammatory Response
Signal Transduction
Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of DNA-templated Transcription
Cellular Response To Lipopolysaccharide
Pathways
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
Activation of NF-kappaB in B cells
RIP-mediated NFkB activation via ZBP1
TAK1-dependent IKK and NF-kappa-B activation
TRAF6 mediated NF-kB activation
Drugs
Diseases
GWAS
Liver enzyme levels (gamma-glutamyl transferase) (
33972514
)
Interacting Genes
6 interacting genes:
CD3E
NFKBIB
POLR1C
POLR1E
TAF1A
UBTF
43 interacting genes:
APP
BAK1
BTBD6
BTRC
CDC25A
CHUK
CSNK2A1
CUL1
DNAJA3
ESR2
FHL3
GIT2
IKBKB
IKBKG
KPNA2
LRPPRC
MCC
MTIF2
NCOR2
NDUFB7
NFKB1
NFKB2
NFKBIA
NGFR
NKIRAS1
NKIRAS2
PDCD2
POLR1A
POLR1B
POLR1C
POLR1D
POLR1E
POLR1G
POLR2H
POLR2L
PPARG
RASAL2
REL
RELA
RXRA
SKP1
TSPAN1
VPS52
Entrez ID
10849
4793
HPRD ID
00125
07260
Ensembl ID
ENSG00000117877
ENSG00000104825
Uniprot IDs
O15446
G5E9C2
Q15653
PDB IDs
7OB9
7OBA
7OBB
7VBA
7VBB
7VBC
8A43
9CK0
Enriched GO Terms of Interacting Partners
?
Transcription By RNA Polymerase I
DNA-templated Transcription
Transcription Initiation At RNA Polymerase I Promoter
Nucleobase-containing Compound Biosynthetic Process
RNA Polymerase I Preinitiation Complex Assembly
RNA Polymerase I Complex
Fibrillar Center
RNA Metabolic Process
Macromolecule Biosynthetic Process
DNA-directed RNA Polymerase Complex
Nucleolus
Transcription Preinitiation Complex Assembly
Nucleic Acid Metabolic Process
DNA-templated Transcription Initiation
RNA Polymerase I General Transcription Initiation Factor Binding
Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential
Maintenance Of Protein Location In Plasma Membrane
RNA Polymerase I Cis-regulatory Region Sequence-specific DNA Binding
Positive Regulation Of Cell Communication By Electrical Coupling
Gamma-delta T Cell Receptor Complex
Nucleobase-containing Compound Metabolic Process
RNA Polymerase I Transcription Regulator Complex
T Cell Anergy
Regulation Of Glucose Mediated Signaling Pathway
Nucleolar Large RRNA Transcription By RNA Polymerase I
Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential
RNA Polymerase I General Transcription Initiation Factor Activity
RNA Polymerase Transcription Factor SL1 Complex
Cellular Response To Magnesium Ion
Positive Regulation Of T Cell Anergy
Positive Regulation Of Cell-cell Adhesion Mediated By Integrin
T Cell Tolerance Induction
Protein-DNA Complex Assembly
Negative Regulation Of Potassium Ion Transmembrane Transporter Activity
Spectrin-associated Cytoskeleton
Channel Activator Activity
Regulation Of Membrane Depolarization During Action Potential
Negative Regulation Of Voltage-gated Potassium Channel Activity
Negative Regulation Of Delayed Rectifier Potassium Channel Activity
Alpha-beta T Cell Receptor Complex
Signal Complex Assembly
Regulation Of T Cell Anergy
Transcription Elongation By RNA Polymerase I
Regulation Of Delayed Rectifier Potassium Channel Activity
CD4-positive, Alpha-beta T Cell Proliferation
RNA Polymerase I Core Promoter Sequence-specific DNA Binding
Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Positive Regulation Of T Cell Tolerance Induction
Positive Regulation Of Membrane Potential
Protein Localization To Axon
RNA Polymerase I Complex
Non-canonical NF-kappaB Signal Transduction
DNA-directed RNA Polymerase Complex
Canonical NF-kappaB Signal Transduction
Nucleoplasm
DNA-directed RNA Polymerase Activity
Intracellular Signal Transduction
Regulation Of Canonical NF-kappaB Signal Transduction
Transcription By RNA Polymerase I
DNA-templated Transcription
Intracellular Signaling Cassette
Negative Regulation Of Canonical NF-kappaB Signal Transduction
I-kappaB/NF-kappaB Complex
Cytosol
Regulation Of Intracellular Signal Transduction
RNA Polymerase III Complex
Regulation Of MiRNA Metabolic Process
Negative Regulation Of Signal Transduction
Nucleobase-containing Compound Biosynthetic Process
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
RRNA Transcription
Tumor Necrosis Factor-mediated Signaling Pathway
IkappaB Kinase Complex
Negative Regulation Of MiRNA Transcription
Regulation Of Signal Transduction
Nucleus
DNA Binding
Macromolecule Biosynthetic Process
Regulation Of MiRNA Transcription
Transferrin Receptor Binding
Signal Transduction Involved In Regulation Of Gene Expression
Immune Response-activating Cell Surface Receptor Signaling Pathway
RNA Metabolic Process
Cellular Response To Tumor Necrosis Factor
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of DNA-binding Transcription Factor Activity
Immune Response-regulating Cell Surface Receptor Signaling Pathway
NF-kappaB P50/p65 Complex
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Response To Cytokine
Response To Peptide
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Response To Tumor Necrosis Factor
Positive Regulation Of T Cell Receptor Signaling Pathway
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