UBE2N and TRIM50

  • Number of citations of the paper that reports this interaction (PMID 21143188)
  • 10
  • Data Source:
  • BioGRID (two hybrid, two hybrid)

UBE2N

TRIM50

Gene Name ubiquitin-conjugating enzyme E2N tripartite motif containing 50
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Protein-Protein Interactions 87 interactors: AMFR ARIH2 AURKA BARD1 BCL10 BFAR BIRC3 BIRC8 BRCA1 CADPS2 CHFR CHUK CNOT4 DTX1 DZIP3 F12 HLTF HSP90AA1 LRSAM1 MALT1 MARCH5 MARCH7 MIB1 MIB2 MID1 MKRN3 MYLIP NBN NEDD4L NEURL1 NFX1 OTUB2 PARK2 PELI1 PELI3 PJA2 RBCK1 RC3H2 RFWD3 RIPK1 RNF103 RNF11 RNF115 RNF122 RNF125 RNF126 RNF128 RNF13 RNF130 RNF152 RNF165 RNF167 RNF182 RNF43 RNF5 RNF8 SH3RF1 SH3RF2 SHPRH SIAH1 SLC2A4 STUB1 TMEM189 TMEM189-UBE2V1 TNFAIP3 TOPORS TP53 TRAF2 TRAF6 TRIM17 TRIM25 TRIM27 TRIM28 TRIM33 TRIM39 TRIM5 TRIM50 TRIM72 UBB UBC UBE2V1 UBE2V2 XIAP ZNRF1 ZNRF2 ZNRF3 ZNRF4 9 interactors: HDAC6 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N
Entrez ID 7334 135892
HPRD ID 04725 15566
Ensembl ID ENSG00000146755
Uniprot IDs P61088 B7ZLG2 Q2M204 Q86XT4
PDB IDs 1J7D 2C2V 3HCT 3HCU 3VON 3W31 4DHI 4DHJ 4DHZ 4EPO 4IP3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
array  c9orf72  carriers  conjugating  consisting  deregulation  discovery  displays  encode  except  expansion  frontotemporal  ftd  generalized  grn  matched  preliminary  proteasomal  proteasome  sabiosciences  sporadic  statistically  ube2e1  ube2i  ube2q1  ube2z  ubiquitin  ubiquitination 
acetylation  acetyltransferases  aggresome  balance  clearance  critical  deacetylase  degradation  dependent  e3  formation  hdac6  identified  interaction  ligase  lys  microtubule  p300  pcaf  polyubiquitinated  promotes  regulates  report  residue  showed  target  tubulin  ubiquitin  ubiquitination 
Tagcloud (Difference) ?
array  c9orf72  carriers  conjugating  consisting  deregulation  discovery  displays  encode  except  expansion  frontotemporal  ftd  generalized  grn  matched  preliminary  proteasomal  proteasome  sabiosciences  sporadic  statistically  ube2e1  ube2i  ube2q1  ube2z 
acetylation  acetyltransferases  aggresome  balance  clearance  critical  deacetylase  degradation  dependent  e3  formation  hdac6  identified  interaction  ligase  lys  microtubule  p300  pcaf  polyubiquitinated  promotes  regulates  report  residue  showed  target  tubulin 
Tagcloud (Intersection) ?
ubiquitin  ubiquitination