TTF1 and BAZ2A

Number of citations of the paper that reports this interaction (PMID 11532953)
70

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		TTF1	BAZ2A
Gene Name		transcription termination factor, RNA polymerase I	bromodomain adjacent to zinc finger domain, 2A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane	Chromatin Silencing Complex Nucleolus RDNA Heterochromatin
	Molecular Function	DNA Binding Chromatin Binding	DNA Binding RNA Binding Protein Binding Zinc Ion Binding Ligand-dependent Nuclear Receptor Binding Lysine-acetylated Histone Binding
	Biological Process	Chromatin Remodeling DNA-templated Transcription, Termination Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Negative Regulation Of DNA Replication Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic	Chromatin Silencing At RDNA DNA Methylation Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Gene Expression Histone Deacetylation Histone H4-K20 Methylation Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Histone H3-K9 Methylation Heterochromatin Assembly Involved In Chromatin Silencing Histone H4 Deacetylation
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression	NoRC negatively regulates rRNA expression Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS			Mean platelet volume ( 22139419) Platelet counts ( 22139419)
Protein-Protein Interactions		6 interactors: BAZ2A KAT2B NFATC3 PTRF SMAD1 SMAD7	7 interactors: DNMT1 DNMT3B HDAC1 HIST1H4A KAT8 SMARCA5 TTF1
Entrez ID		7270	11176
HPRD ID		02866	10417
Ensembl ID		ENSG00000125482	ENSG00000076108
Uniprot IDs		Q15361	F8VU39 J3KPG5 Q9UIF9
PDB IDs			4LZ2
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Initiation Transcription Initiation From RNA Polymerase I Promoter Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase I Promoter Histone H3-K9 Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated BMP Signaling Pathway Nitrogen Compound Metabolic Process Heart Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Heterochromatin Assembly Involved In Chromatin Silencing Gene Silencing Positive Regulation Of Cellular Biosynthetic Process Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Tissue Morphogenesis Mesonephros Development Regulation Of Transcription From RNA Polymerase II Promoter Tube Development Histone H3-K9 Acetylation Regulation Of Protein ADP-ribosylation Transforming Growth Factor Beta Receptor Signaling Pathway Kidney Epithelium Development N-terminal Peptidyl-lysine Acetylation Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Transforming Growth Factor Beta Stimulus Chromatin Remodeling Cardiovascular System Development Response To Transforming Growth Factor Beta Cardiac Muscle Tissue Development	Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Chromatin Modification Chromatin Organization Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA Methylation On Cytosine Gene Silencing Negative Regulation Of Cellular Metabolic Process Chromatin Silencing Chromatin Remodeling C-5 Methylation Of Cytosine DNA Methylation ATP-dependent Chromatin Remodeling Organelle Organization Gene Expression DNA Modification Negative Regulation Of Histone H3-K9 Methylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Histone H3-K4 Methylation Chromatin Silencing At RDNA Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Histone Methylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Histone H3-K4 Methylation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression CENP-A Containing Nucleosome Assembly DNA-templated Transcription, Initiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Histone Exchange DNA Replication-independent Nucleosome Assembly Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Histone Methylation Centromere Complex Assembly Regulation Of Histone Methylation DNA Metabolic Process Cellular Response To Amino Acid Stimulus Histone Modification
Tagcloud ?		able activate binds cotransfection differentiation essential experiments finding hormone importance main maintenance markers minimal modulation mutated nonthyroid promoter promoters shows step strengthens thyroglobulin thyroid thyroperoxidase trans transcription tsh tshr	bc bladder characterizing fgfr3 formulation lowered messenger micrornas mir mirna mtor oncogenes oncogenesis oncomir ploidy promoted promoting qrt representative respective rnas rt4 smarca5 supposed t24 thap2 today transfection urothelial
Tagcloud (Difference) ?		able activate binds cotransfection differentiation essential experiments finding hormone importance main maintenance markers minimal modulation mutated nonthyroid promoter promoters shows step strengthens thyroglobulin thyroid thyroperoxidase trans transcription tsh tshr	bc bladder characterizing fgfr3 formulation lowered messenger micrornas mir mirna mtor oncogenes oncogenesis oncomir ploidy promoted promoting qrt representative respective rnas rt4 smarca5 supposed t24 thap2 today transfection urothelial
Tagcloud (Intersection) ?