TRHR and SLC39A9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRHR	SLC39A9
Description		thyrotropin releasing hormone receptor	solute carrier family 39 member 9
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus Cytoplasm Mitochondrion Golgi Apparatus Trans-Golgi Network Plasma Membrane Membrane Mitochondrial Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	G Protein-coupled Receptor Activity Thyrotropin-releasing Hormone Receptor Activity Protein Binding	G Protein-coupled Receptor Activity Zinc Ion Transmembrane Transporter Activity Androgen Binding Protein Binding Zinc Efflux Transmembrane Transporter Activity Metal Ion Transmembrane Transporter Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway	Monoatomic Ion Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis G Protein-coupled Receptor Signaling Pathway Metal Ion Transport Transmembrane Transport Bicellular Tight Junction Assembly Zinc Ion Transmembrane Transport Regulation Of Vascular Endothelial Cell Proliferation Regulation Of Cellular Response To Testosterone Stimulus
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events
Drugs		Protirelin
Diseases
GWAS		Body mass (lean) ( 19268274) Daytime sleep phenotypes ( 27126917) LDL cholesterol levels ( 32203549) Night sleep phenotypes ( 27126917) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969)	Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		19 interacting genes: ARRB1 C1QL4 COMT EFNA5 FAM241B FXYD6-FXYD2 GJB2 IER3IP1 NIPAL4 PEDS1-UBE2V1 SLC39A2 SLC39A9 SLC41A1 TMEFF2 TMEM218 TMEM239 TRH UBE2J1 YIPF6	40 interacting genes: ANKRD46 APH1A AQP6 BNIP2 CBARP CD79A CERS3 CPLX4 CRB3 CREB3L1 CREB3L3 CYB5B ELOVL5 EVI2B FCER1G FFAR2 GJA8 GPR101 HERPUD2 HTR2C LNPEP MANBAL MGST3 NEU1 RTP2 SERINC2 SLC10A6 SLC16A2 SLC39A2 SLC61A1 SLC66A1 SLC71A2 SLC7A1 SSMEM1 TM4SF18 TMEM140 TMEM237 TMEM86B TRHR VMP1
Entrez ID		7201	55334
HPRD ID		11767	15387
Ensembl ID		ENSG00000174417	ENSG00000029364
Uniprot IDs		P34981	B4DDK0 C4N9M8 M0QX28 Q9NUM3
PDB IDs		7WKD 7X1T 7X1U 7XW9
Enriched GO Terms of Interacting Partners?		Magnesium Ion Transport Magnesium Ion Transmembrane Transport Magnesium Ion Transmembrane Transporter Activity Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Metal Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport	Membrane Lysine Transport Plasma Membrane Positive Regulation Of Acute Inflammatory Response L-lysine Transmembrane Transporter Activity L-histidine Transmembrane Transporter Activity L-histidine Transmembrane Transport L-lysine Transmembrane Transport Regulation Of Acute Inflammatory Response Basic Amino Acid Transmembrane Transporter Activity L-arginine Transmembrane Transporter Activity Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Aromatic Amino Acid Transport L-arginine Transmembrane Transport Azole Transmembrane Transport Endoplasmic Reticulum Membrane Basic Amino Acid Transmembrane Transport Protein Binding Transmembrane Transport Amino Acid Transmembrane Transport Basic Amino Acid Transport Response To Unfolded Protein Phospholipid Scramblase Activity Plasma Membrane Phospholipid Scrambling
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