TRHR

Gene Name		thyrotropin-releasing hormone receptor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Thyrotropin-releasing Hormone Receptor Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Body mass (lean) ( 19268274)
Protein-protein Interactions		2 interactors: ARRB1 TRH
Entrez ID		7201
HPRD ID		11767
Ensembl ID		ENSG00000174417
Uniprot IDs		P34981
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Insulin Secretion Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Positive Regulation Of Hormone Secretion Positive Regulation Of Protein Secretion Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion Regulation Of Hormone Secretion Positive Regulation Of Secretion Positive Regulation Of Protein Transport Histamine Metabolic Process Regulation Of Protein Secretion Negative Regulation Of Feeding Behavior Negative Regulation Of Glutamate Secretion Positive Regulation Of Gamma-aminobutyric Acid Secretion Positive Regulation Of Histone H4 Acetylation Regulation Of Protein Transport Regulation Of Secretion Regulation Of Establishment Of Protein Localization Positive Regulation Of Amino Acid Transport Positive Regulation Of Transport Regulation Of Glutamate Secretion G-protein Coupled Receptor Internalization Regulation Of Protein Localization Regulation Of Feeding Behavior Negative Regulation Of Interleukin-8 Production Stress Fiber Assembly Regulation Of Histone H4 Acetylation Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Receptor Internalization Positive Regulation Of Histone Acetylation Regulation Of Cellular Localization Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Response To Abiotic Stimulus Eating Behavior Regulation Of Receptor Internalization Response To Corticosterone Positive Regulation Of Rho Protein Signal Transduction Negative Regulation Of Interleukin-6 Production Positive Regulation Of Receptor-mediated Endocytosis Response To Mineralocorticoid Receptor Internalization Regulation Of Histone Acetylation Adult Walking Behavior Positive Regulation Of Ras Protein Signal Transduction Response To Cold Positive Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
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