TRHR and PEDS1-UBE2V1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRHR	PEDS1-UBE2V1
Description		thyrotropin releasing hormone receptor	PEDS1-UBE2V1 readthrough
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Thyrotropin-releasing Hormone Receptor Activity Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events
Drugs		Protirelin
Diseases
GWAS		Body mass (lean) ( 19268274) Daytime sleep phenotypes ( 27126917) LDL cholesterol levels ( 32203549) Night sleep phenotypes ( 27126917) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969)
Interacting Genes		19 interacting genes: ARRB1 C1QL4 COMT EFNA5 FAM241B FXYD6-FXYD2 GJB2 IER3IP1 NIPAL4 PEDS1-UBE2V1 SLC39A2 SLC39A9 SLC41A1 TMEFF2 TMEM218 TMEM239 TRH UBE2J1 YIPF6	17 interacting genes: AQP6 CNR2 CREB3L1 FAM209A GPR152 PGRMC2 SLC10A1 SLC10A6 SLC18A3 SLC30A4 STOM TMEM31 TMEM52B TMX2 TRAF6 TRHR UBE2N
Entrez ID		7201	387522
HPRD ID		11767	11926
Ensembl ID		ENSG00000174417	ENSG00000124208
Uniprot IDs		P34981	I3L0A0
PDB IDs		7WKD 7X1T 7X1U 7XW9
Enriched GO Terms of Interacting Partners?		Magnesium Ion Transport Magnesium Ion Transmembrane Transport Magnesium Ion Transmembrane Transporter Activity Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Metal Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport	Bile Acid:sodium Symporter Activity Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Monoatomic Ion Transport Bile Acid And Bile Salt Transport
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