SNUPN and ZPR1

Number of citations of the paper that reports this interaction (PubMedID 12095920)
66

Data Source:
BioGRID (pull down)

		SNUPN	ZPR1
Description		snurportin 1	ZPR1 zinc finger
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Plasma Membrane NLS-dependent Protein Nuclear Import Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cajal Body Axon Growth Cone Cell Projection Neuronal Cell Body Perikaryon Perinuclear Region Of Cytoplasm Gemini Of Cajal Bodies
	Molecular Function	RNA Cap Binding RNA Binding Protein Binding Nuclear Import Signal Receptor Activity	Protein Binding Zinc Ion Binding Receptor Tyrosine Kinase Binding Translation Initiation Factor Binding Protein Folding Chaperone Metal Ion Binding
	Biological Process	RNA Import Into Nucleus Protein Import Into Nucleus Cytoskeleton Organization Protein Complex Oligomerization Protein Tetramerization SnRNA Import Into Nucleus	Microtubule Cytoskeleton Organization Inner Cell Mass Cell Proliferation Trophectodermal Cell Proliferation DNA Replication MRNA Processing Protein Folding Signal Transduction RNA Splicing Positive Regulation Of Gene Expression Spinal Cord Development Cell Differentiation Cajal Body Organization Regulation Of Myelination Positive Regulation Of RNA Splicing DNA Endoreduplication Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Cell Cycle Positive Regulation Of Growth Axon Development Cellular Response To Epidermal Growth Factor Stimulus Apoptotic Process Involved In Development Pre-mRNA Catabolic Process Negative Regulation Of Motor Neuron Apoptotic Process
Pathways		snRNP Assembly
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Hip circumference adjusted for BMI ( 34021172)	Aspartate aminotransferase levels ( 33547301) Cholesterol ( 31902109) Coronary artery disease ( 29212778 29263402) Delirium ( 29631748) Fasting triglyceride levels ( 32603185) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) High density lipoprotein cholesterol levels ( 29403010) Low density lipoprotein cholesterol levels ( 29403010) Metabolic syndrome ( 30382898 31589552) Myocardial infarction ( 33532862) Postprandial triglyceride levels ( 32603185) Postprandial triglyceride response to high fat diet meal ( 26256467) Total cholesterol levels ( 29615537) Triglyceride levels ( 29615537) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		15 interacting genes: DBN1 DDX20 ENO2 GCNT3 KPNB1 MEX3B PAFAH1B2 PEX5 RNF126 RPL17 SMN1 SNRPB TNNT3 XPO1 ZPR1	7 interacting genes: CDK5RAP2 EEF1A1 EGFR MPP3 OGT SNUPN SUMO4
Entrez ID		10073	8882
HPRD ID		07441	04877
Ensembl ID		ENSG00000169371	ENSG00000109917
Uniprot IDs		O95149	O75312
PDB IDs		1XK5 2P8Q 2Q5D 2QNA 3GB8 3GJX 3LWW 3NBY 3NBZ 3NC0 5DIS
Enriched GO Terms of Interacting Partners?		Gemini Of Cajal Bodies SMN-Sm Protein Complex Growth Cone Spliceosomal SnRNP Assembly Cajal Body SMN Complex Cytoplasm Regulation Of Nucleocytoplasmic Transport Cerebral Cortex Neuron Differentiation Perikaryon Regulation Of Intracellular Protein Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway RNA Splicing Cerebral Cortex Cell Migration Cytosol Negative Regulation Of ERBB Signaling Pathway Cell Cortex Positive Regulation Of Dendritic Spine Development Protein-containing Complex Forebrain Neuron Differentiation Positive Regulation Of Protein Import Into Nucleus MRNA Processing Telencephalon Cell Migration Forebrain Cell Migration Negative Regulation Of Core Promoter Binding Spliceosomal Complex Assembly Protein-RNA Complex Assembly Positive Regulation Of Calcium-dependent ATPase Activity DNA Endoreduplication Pre-mRNA Catabolic Process Acetylgalactosaminyl-O-glycosyl-glycoprotein Beta-1,6-N-acetylglucosaminyltransferase Activity Regulation Of Dendritic Spine Development Protein Domain Specific Binding Protein Monoubiquitination Cell Communication By Chemical Coupling Synaptic Membrane RNA Binding Nuclear Membrane Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cajal-Retzius Cell Differentiation Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Intracellular Transport Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding U2 SnRNP Binding Cellular Response To Triglyceride N-acetyllactosaminide Beta-1,6-N-acetylglucosaminyltransferase Activity Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,6-N-acetylglucosaminyltransferase Activity	Kinase Binding Clathrin-coated Endocytic Vesicle Membrane Response To Epidermal Growth Factor Regulation Of Protein Catabolic Process Cellular Response To Epidermal Growth Factor Stimulus Multivesicular Body, Internal Vesicle Lumen Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly
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