SNUPN and KPNB1

Number of citations of the paper that reports this interaction (PMID 12095920)
29

Data Source:
HPRD (in vivo, in vitro)

		SNUPN	KPNB1
Gene Name		snurportin 1	karyopherin (importin) beta 1
Image
Gene Ontology Annotations	Cellular Component	Nuclear Pore Cytosol Extracellular Vesicular Exosome	Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Membrane Extracellular Vesicular Exosome Endoplasmic Reticulum Tubular Network
	Molecular Function	RNA Cap Binding Protein Transporter Activity	Protein Binding Nuclear Localization Sequence Binding Zinc Ion Binding Ran GTPase Binding Protein Transporter Activity Enzyme Binding Protein Domain Specific Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal SnRNP Assembly Protein Import Into Nucleus Gene Expression NcRNA Metabolic Process SnRNA Import Into Nucleus	Protein Import Into Nucleus, Translocation Apoptotic DNA Fragmentation Protein Import Into Nucleus NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Viral Process Viral Life Cycle Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Intracellular Transport Of Virus
Pathways		snRNP Assembly Metabolism of non-coding RNA	Metabolism of lipids and lipoproteins ISG15 antiviral mechanism Nuclear import of Rev protein HIV Infection Interferon Signaling Apoptotic execution phase Host Interactions of HIV factors Cytokine Signaling in Immune system Interactions of Rev with host cellular proteins Influenza Infection Antiviral mechanism by IFN-stimulated genes Influenza Life Cycle Regulation of cholesterol biosynthesis by SREBP (SREBF) Activation of DNA fragmentation factor Transport of Ribonucleoproteins into the Host Nucleus Apoptosis induced DNA fragmentation Programmed Cell Death
Drugs
Diseases
GWAS			Multiple sclerosis ( 22190364)
Protein-Protein Interactions		16 interactors: DBN1 DDX20 ENO2 GCNT3 KPNB1 MEX3B PAFAH1B2 PEX5 RAN RNF126 RPL17 SMN1 SNRPB TNNT3 XPO1 ZPR1	59 interactors: AMFR CD99 CHD3 CSE1L CSNK1A1 CUL4B ELAVL1 EXO1 FGFR1 H1F0 HIST1H1C IGFBP3 IGFBP5 IPO7 IPO8 KPNA1 KPNA2 KPNA3 KPNA4 KPNA6 LYST MESDC2 MSL1 NFATC1 NFYA NUP153 NUP50 NUP54 NUP62 NUP98 NUTF2 PIAS4 PLCD1 PRKD3 PTHLH PTMA PTN PTPN2 RAN RANBP1 RANBP2 RCC1 RPL5 RUNX1T1 SMAD2 SMAD3 SMN1 SMNDC1 SNUPN SOX9 SREBF2 SRY TAF3 TAF8 TERF1 TP53 TUBA1A UBR5 VIMP
Entrez ID		10073	3837
HPRD ID		07441	04114
Ensembl ID		ENSG00000169371
Uniprot IDs		C9K0X5 O95149	B7Z752 B7ZAV6 Q14974
PDB IDs		1XK5 2P8Q 2Q5D 2QNA 3GB8 3GJX 3LWW 3NBY 3NBZ 3NC0	1F59 1IBR 1M5N 1O6O 1O6P 1QGK 1QGR 2P8Q 2Q5D 2QNA 3LWW
Enriched GO Terms of Interacting Partners?		Intracellular Transport Of Virus Ribosomal Small Subunit Export From Nucleus Ribonucleoprotein Complex Biogenesis Spliceosomal SnRNP Assembly Viral Life Cycle Ribosomal Large Subunit Export From Nucleus Protein Localization To Organelle Ribosomal Subunit Export From Nucleus MRNA Metabolic Process Cytoplasmic Transport Establishment Of Protein Localization To Organelle RNA Splicing Catabolic Process Protein Import Protein Targeting MRNA Processing Cellular Protein Localization Protein Localization To Nucleus Ribonucleoprotein Complex Assembly Protein Export From Nucleus Intracellular Protein Transport Intracellular Transport Viral Process MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing, Via Transesterification Reactions Cellular Localization Nucleocytoplasmic Transport Nuclear Transport Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process Pre-mRNA Catabolic Process DNA Endoreduplication Protein Localization Establishment Of Localization In Cell Cajal Body Organization Negative Regulation Of Protein Homotetramerization Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Trophectodermal Cell Proliferation Protein Transport Metabolic Process Protein Import Into Peroxisome Matrix, Translocation Cell Communication By Chemical Coupling Negative Regulation Of Motor Neuron Apoptotic Process Establishment Of Protein Localization Cellular Macromolecule Catabolic Process Nuclear Export Protein Import Into Peroxisome Matrix, Docking Immunoglobulin Production In Mucosal Tissue Protein Import Into Nucleus Nuclear Import	Nucleocytoplasmic Transport Nuclear Transport Nuclear Import Protein Localization To Nucleus Protein Import Into Nucleus Viral Process Cytoplasmic Transport Protein Import Intracellular Transport Protein Localization Protein Transport Establishment Of Protein Localization Cellular Localization Establishment Of Localization In Cell Protein Localization To Organelle Protein Targeting Cellular Protein Localization Intracellular Protein Transport Establishment Of Protein Localization To Organelle Viral Life Cycle Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Nuclear Envelope Disassembly Cellular Nitrogen Compound Metabolic Process Nuclear Envelope Disassembly Gene Expression Cellular Response To Cytokine Stimulus Cell Cycle NLS-bearing Protein Import Into Nucleus Cell Cycle Process Viral Transcription Regulation Of Glucose Transport RNA Metabolic Process Cellular Response To Organic Substance Mitotic Cell Cycle Process Nitrogen Compound Metabolic Process Cytokine-mediated Signaling Pathway Response To Cytokine Cellular Response To Stimulus Nuclear Envelope Organization RNA Biosynthetic Process Mitotic Cell Cycle Glucose Transport Cellular Metabolic Process Hexose Transport Signal Transduction RNA Transport RNA Localization Response To Organic Substance
Tagcloud ?			30d enhancer ezh2 forced homologue immunohistochemical importantly malignancies mir mpnst mpnsts negatively nerve neurofibromatosis nodes polycomb recur represents rescues sheath signalling sporadically suppresses targetable tumourigenesis tumourigenicity tumours utr zeste
Tagcloud (Difference) ?			30d enhancer ezh2 forced homologue immunohistochemical importantly malignancies mir mpnst mpnsts negatively nerve neurofibromatosis nodes polycomb recur represents rescues sheath signalling sporadically suppresses targetable tumourigenesis tumourigenicity tumours utr zeste
Tagcloud (Intersection) ?