TNNC2 and TNNI2

Number of citations of the paper that reports this interaction (PMID 9560191)
29

Data Source:
HPRD (in vitro)

		TNNC2	TNNI2
Gene Name		troponin C type 2 (fast)	troponin I type 2 (skeletal, fast)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Troponin Complex	Nucleus Cytosol Troponin Complex
	Molecular Function	Actin Binding Calcium Ion Binding	Actin Binding Protein Binding Troponin T Binding
	Biological Process	Skeletal Muscle Contraction Regulation Of Muscle Contraction Muscle Filament Sliding	Skeletal Muscle Contraction Regulation Of Muscle Contraction Muscle Filament Sliding Positive Regulation Of Transcription, DNA-templated
Pathways		Striated Muscle Contraction	Striated Muscle Contraction
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		2 interactors: TNNI2 TNNI3	13 interactors: ACTB CALM1 ESRRA HNF4G PKD2L1 RORB TNNC1 TNNC2 TNNT1 TNNT3 TRIM55 TRIM63 UPF2
Entrez ID		7125	7136
HPRD ID		08929	01843
Ensembl ID		ENSG00000101470	ENSG00000130598
Uniprot IDs		P02585 Q6FH92	P48788
PDB IDs
Enriched GO Terms of Interacting Partners?		Muscle Filament Sliding Actin-myosin Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Striated Muscle Contraction Regulation Of Muscle Contraction Muscle Contraction Muscle System Process Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Negative Regulation Of ATPase Activity Actin Filament-based Process Neurological System Process Involved In Regulation Of Systemic Arterial Blood Pressure Skeletal Muscle Contraction Regulation Of ATPase Activity Musculoskeletal Movement Ventricular Cardiac Muscle Tissue Morphogenesis Movement Of Cell Or Subcellular Component Cardiac Muscle Contraction Regulation Of Smooth Muscle Contraction Ventricular Cardiac Muscle Tissue Development Cardiac Muscle Tissue Morphogenesis Muscle Tissue Morphogenesis Heart Contraction Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis Regulation Of Systemic Arterial Blood Pressure Vasculogenesis Cardiac Ventricle Development Cardiac Chamber Development Regulation Of Blood Pressure Cardiac Muscle Tissue Development	Muscle Contraction Skeletal Muscle Contraction Actin-myosin Filament Sliding Muscle Filament Sliding Muscle System Process Musculoskeletal Movement Actin-mediated Cell Contraction Regulation Of Muscle Contraction Actin Filament-based Movement Striated Muscle Contraction Cellular Response To Steroid Hormone Stimulus Response To Steroid Hormone Steroid Hormone Mediated Signaling Pathway Cellular Response To Organic Cyclic Compound Hormone-mediated Signaling Pathway Response To Lipid Cellular Response To Lipid Response To Organic Cyclic Compound Response To Hormone Transcription Initiation From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Substantia Nigra Development Cellular Response To Hormone Stimulus Regulation Of ATPase Activity DNA-templated Transcription, Initiation Actin Filament-based Process Neural Nucleus Development Organ Development Regulation Of Muscle Filament Sliding Speed Movement Of Cell Or Subcellular Component Regulation Of Striated Muscle Contraction Midbrain Development Detection Of Chemical Stimulus Involved In Sensory Perception Of Sour Taste Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Muscle Filament Sliding Diaphragm Contraction Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of Osteoblast Differentiation Cellular Response To Organic Substance Signal Transduction Amacrine Cell Differentiation Regulation Of High Voltage-gated Calcium Channel Activity Sensory Perception Of Sour Taste Involuntary Skeletal Muscle Contraction System Development Skeletal Muscle Atrophy Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Response To Glucocorticoid
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