TM7SF2 and RAP2A

Number of citations of the paper that reports this interaction (PubMedID 18624398)
0

Data Source:
BioGRID (two hybrid)

		TM7SF2	RAP2A
Description		transmembrane 7 superfamily member 2	RAP2A, member of RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Inner Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Organelle Membrane Receptor Complex	Lysosome Endosome Golgi Apparatus Cytosol Plasma Membrane Endomembrane System Membrane Midbody Cytoplasmic Vesicle Membrane Lamellipodium Membrane Endolysosome Cell Projection Synapse Recycling Endosome Recycling Endosome Membrane Synaptic Membrane Bounding Membrane Of Organelle Schaffer Collateral - CA1 Synapse
	Molecular Function	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-CH Group Of Donors, NAD Or NADP As Acceptor Delta14-sterol Reductase Activity NADP Binding	Nucleotide Binding Magnesium Ion Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Cholesterol Biosynthetic Process Steroid Metabolic Process Cholesterol Metabolic Process Sterol Biosynthetic Process	Signal Transduction Intracellular Protein Localization Actin Cytoskeleton Organization Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Rap Protein Signal Transduction Establishment Of Protein Localization Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Regulation Of Synapse Assembly Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Positive Regulation Of Microvillus Assembly
Pathways		Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP) Cholesterol biosynthesis via lathosterol
Drugs			Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS			Gut microbiota (bacterial taxa) ( 27723756) Peripheral artery disease ( 26488411)
Interacting Genes		4 interacting genes: CHRM4 CYSRT1 LCE2C RAP2A	32 interacting genes: ACVR1 AFDN ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 NEDD4 PLG RAB40B RAF1 RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK
Entrez ID		7108	5911
HPRD ID		04564	01547
Ensembl ID		ENSG00000149809	ENSG00000125249
Uniprot IDs		O76062	P10114
PDB IDs			1KAO 2RAP 3RAP
Enriched GO Terms of Interacting Partners?		G Protein-coupled Acetylcholine Receptor Activity Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Rap Protein Signal Transduction Endolysosome Regulation Of Microvillus Assembly Positive Regulation Of Microvillus Assembly Epidermis Development	Intracellular Signaling Cassette Signal Transduction Transforming Growth Factor Beta Receptor Activity, Type I Intracellular Signal Transduction Ras Protein Signal Transduction Small GTPase-mediated Signal Transduction Transmembrane Receptor Protein Serine/threonine Kinase Activity Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling GTPase Regulator Activity Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Microvillus Assembly Protein Kinase Activity Establishment Of Endothelial Barrier Activin Receptor Complex Activin Receptor Activity, Type I NMDA Glutamate Receptor Activity Glutamate Binding Endothelial Cell Development Guanyl-nucleotide Exchange Factor Activity BMP Receptor Activity Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition SMAD Binding NMDA Selective Glutamate Receptor Complex Glutamate-gated Calcium Ion Channel Activity Positive Regulation Of Signal Transduction Kinase Activity Potassium Channel Inhibitor Activity Excitatory Chemical Synaptic Transmission Regulation Of Microvillus Assembly Activin Binding Cellular Response To Growth Factor Stimulus Enzyme-linked Receptor Protein Signaling Pathway Plasma Membrane Regulation Of Type B Pancreatic Cell Proliferation Regulation Of Intracellular Signal Transduction Protein Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Signal Transduction Nucleotide Binding Regulation Of Insulin Secretion Response To Growth Factor Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Osteoblast Differentiation Regulation Of Cartilage Development Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway I-SMAD Binding Positive Regulation Of Cellular Component Biogenesis
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?