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TM7SF2

Description transmembrane 7 superfamily member 2
Image No pdb structure
GO Annotations Cellular Component
  • Nuclear Inner Membrane
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Plasma Membrane
  • Membrane
  • Organelle Membrane
  • Receptor Complex
Molecular Function
  • Protein Binding
  • Oxidoreductase Activity
  • Oxidoreductase Activity, Acting On The CH-CH Group Of Donors, NAD Or NADP As Acceptor
  • Delta14-sterol Reductase Activity
  • NADP Binding
Biological Process
  • Lipid Metabolic Process
  • Steroid Biosynthetic Process
  • Cholesterol Biosynthetic Process
  • Steroid Metabolic Process
  • Cholesterol Metabolic Process
  • Sterol Biosynthetic Process
Pathways
  • Cholesterol biosynthesis
  • Activation of gene expression by SREBF (SREBP)
  • Cholesterol biosynthesis via lathosterol
Drugs
Diseases
GWAS
Interacting Genes 4 interacting genes: CHRM4 CYSRT1 LCE2C RAP2A
Entrez ID 7108
HPRD ID 04564
Ensembl ID ENSG00000149809
Uniprot IDs O76062
PDB IDs
Enriched GO Terms of Interacting Partners?
  • G Protein-coupled Acetylcholine Receptor Activity
  • Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway
  • Rap Protein Signal Transduction
  • Endolysosome
  • Regulation Of Microvillus Assembly
  • Positive Regulation Of Microvillus Assembly
  • Epidermis Development
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