TFB1M and POLRMT

Number of citations of the paper that reports this interaction (PubMedID 12068295)
0

Data Source:
HPRD (in vitro)

		TFB1M	POLRMT
Description		transcription factor B1, mitochondrial	RNA polymerase mitochondrial
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid	DNA-directed RNA Polymerase Complex Mitochondrion Mitochondrial Matrix Protein-containing Complex Mitochondrial DNA-directed RNA Polymerase Complex Mitochondrial Nucleoid
	Molecular Function	RRNA (adenine-N6,N6-)-dimethyltransferase Activity DNA Binding RNA Binding Protein Binding Methyltransferase Activity Transferase Activity Mitochondrial Transcription Factor Activity S-adenosyl-L-methionine Binding	3'-5'-RNA Exonuclease Activity Mitochondrial Promoter Sequence-specific DNA Binding DNA Binding RNA Binding DNA-directed RNA Polymerase Activity Protein Binding Transferase Activity Nucleotidyltransferase Activity 5'-3' RNA Polymerase Activity Sequence-specific DNA Binding
	Biological Process	RRNA Modification RRNA Processing Transcription Initiation At Mitochondrial Promoter RRNA Methylation Methylation	Mitochondrial DNA Replication DNA-templated Transcription Mitochondrial Transcription Transcription Initiation At Mitochondrial Promoter
Pathways		Transcriptional activation of mitochondrial biogenesis rRNA modification in the mitochondrion	Mitochondrial transcription initiation Transcriptional activation of mitochondrial biogenesis Strand-asynchronous mitochondrial DNA replication
Drugs
Diseases
GWAS		Dimensional psychopathology (Arousal) ( 29496196) Dimensional psychopathology (Negative) ( 29496196) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Metabolite levels ( 23823483) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		2 interacting genes: POLRMT TFAM	3 interacting genes: TFB1M TFB2M UBC
Entrez ID		51106	5442
HPRD ID		09515	03468
Ensembl ID		ENSG00000029639	ENSG00000099821
Uniprot IDs		E5KTM5 Q8WVM0	O00411 Q4G0F4
PDB IDs		6AAX 6AJK 8CSP 8CSQ 8CSR 8CSU	3SPA 4BOC 5OLA 6ERP 6ERQ 7A8P 7PZP 7PZR 7ZC4 8U8U 8U8V 9BDC 9BDD
Enriched GO Terms of Interacting Partners?		Mitochondrial Promoter Sequence-specific DNA Binding Transcription Initiation At Mitochondrial Promoter Mitochondrial Transcription Mitochondrial Nucleoid Mitochondrial RNA Metabolic Process DNA-templated Transcription Initiation Mitochondrial DNA-directed RNA Polymerase Complex Macromolecule Biosynthetic Process Mitochondrial Transcription Factor Activity Vascular Endothelial Growth Factor Receptor 1 Binding Vascular Endothelial Growth Factor Receptor Binding Response To Decreased Oxygen Levels Response To Hypoxia Positive Regulation Of Vascular Wound Healing Positive Regulation Of Mast Cell Chemotaxis Response To Oxygen Levels 5'-3' RNA Polymerase Activity Regulation Of Mast Cell Chemotaxis Mitochondrial Matrix DNA-templated Transcription Mitochondrial DNA Replication Sequence-specific DNA Binding Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Vascular Wound Healing Induction Of Positive Chemotaxis Positive Regulation Of Vascular Permeability Mitochondrial DNA Metabolic Process Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Positive Chemotaxis Coronary Vasculature Development DNA-directed RNA Polymerase Activity 3'-5'-RNA Exonuclease Activity Protein-containing Complex Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Chemoattractant Activity DNA-directed RNA Polymerase Complex Sprouting Angiogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Nucleobase-containing Compound Biosynthetic Process Cardiac Muscle Contraction Positive Chemotaxis Regulation Of Vascular Permeability DNA-templated DNA Replication Transcription Coactivator Binding Positive Regulation Of Peptidyl-tyrosine Phosphorylation Heat Shock Protein Binding Positive Regulation Of Wound Healing Platelet Alpha Granule Lumen	RRNA (adenine-N6,N6-)-dimethyltransferase Activity Mitochondrial Transcription Factor Activity Transcription Initiation At Mitochondrial Promoter RRNA Methylation RRNA Modification Mitochondrial RNA Metabolic Process Mitochondrial Nucleoid DNA-templated Transcription Initiation RNA Methylation Macromolecule Methylation RNA Modification Methyltransferase Activity Methylation RRNA Processing RRNA (adenine-N6-)-methyltransferase Activity RRNA Metabolic Process RNA Binding Mitochondrion Mitochondrial Transcription Mitochondrial Matrix Protein Tag Activity S-adenosyl-L-methionine Binding RNA Processing Nucleobase-containing Compound Biosynthetic Process Endocytic Vesicle Membrane RNA Metabolic Process Macromolecule Biosynthetic Process Macromolecule Metabolic Process
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