VGLL2 and TEAD1

Number of citations of the paper that reports this interaction (PMID 12376544)
26

Data Source:
HPRD (in vivo, in vitro)

		VGLL2	TEAD1
Gene Name		vestigial-like family member 2	TEA domain family member 1 (SV40 transcriptional enhancer factor)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cytoplasm Golgi Apparatus
	Molecular Function	Transcription Coactivator Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Transcription, DNA-templated Skeletal Muscle Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Gene Expression Hippo Signaling
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS		Height ( 20881960)	Height ( 20881960)
Protein-Protein Interactions		3 interactors: MEF2C TEAD1 TEAD3	17 interactors: GCAT HLA-DMB INSR MAX MEF2A MEF2BNB-MEF2B MEF2C MYH7 NCOA1 SRF TBP UBTD1 VGLL1 VGLL2 VGLL4 YAP1 ZDHHC17
Entrez ID		245806	7003
HPRD ID		18282	01802
Ensembl ID		ENSG00000170162	ENSG00000187079
Uniprot IDs		Q8N8G2	A4FUP2 P28347 Q59EF3
PDB IDs			2HZD 3KYS
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Stem Cell Maintenance Regulation Of Stem Cell Maintenance Hippo Signaling Positive Regulation Of Cell Development Positive Regulation Of Stem Cell Differentiation Embryonic Heart Tube Morphogenesis Embryonic Heart Tube Development Regulation Of Cell Development Positive Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Mesenchyme Development Primary Heart Field Specification Sinoatrial Valve Morphogenesis Regulation Of Synaptic Activity Cellular Response To Trichostatin A Heart Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Muscle Cell Fate Determination Nephron Tubule Epithelial Cell Differentiation Positive Regulation Of Cell Proliferation In Bone Marrow Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Signal Transduction Embryonic Organ Morphogenesis Positive Regulation Of Behavioral Fear Response Positive Regulation Of Macrophage Apoptotic Process Epithelial Tube Morphogenesis Positive Regulation Of Protein Homodimerization Activity Cellular Response To Parathyroid Hormone Stimulus Transcription, DNA-templated Tube Morphogenesis Positive Regulation Of Myeloid Cell Apoptotic Process Ventricular Cardiac Myofibril Assembly RNA Biosynthetic Process Positive Regulation Of Skeletal Muscle Cell Differentiation Cardiac Ventricle Formation Embryonic Organ Development Positive Regulation Of Cellular Metabolic Process Cardiac Chamber Formation Morphogenesis Of An Epithelium Heart Development Germinal Center Formation Lateral Mesoderm Development	Heart Morphogenesis Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Developmental Growth Embryonic Heart Tube Morphogenesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Embryonic Heart Tube Development Platelet Formation Positive Regulation Of Growth Platelet Morphogenesis Biosynthetic Process Cardiac Myofibril Assembly Primary Heart Field Specification Sinoatrial Valve Morphogenesis Regulation Of Synaptic Activity Cellular Response To Trichostatin A RNA Metabolic Process Heart Development Transcription From RNA Polymerase II Promoter Regulation Of Developmental Growth Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nephron Tubule Epithelial Cell Differentiation Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Muscle Cell Fate Determination Gene Expression Striated Muscle Tissue Development Regulation Of RNA Metabolic Process Muscle Tissue Development Positive Regulation Of Macromolecule Biosynthetic Process Cardiac Chamber Development Positive Regulation Of Cell Proliferation In Bone Marrow Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Behavioral Fear Response Positive Regulation Of Organ Growth Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Tissue Development Ventricular Cardiac Myofibril Assembly Smooth Muscle Cell Differentiation Cardiac Muscle Tissue Development Heart Looping Determination Of Heart Left/right Asymmetry Positive Regulation Of Protein Homodimerization Activity Positive Regulation Of Transcription, DNA-templated Cardiac Muscle Cell Development Embryonic Organ Development
Tagcloud ?			520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Difference) ?			520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Intersection) ?