TDO2 and MOB1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TDO2	MOB1A
Description		tryptophan 2,3-dioxygenase	MOB kinase activator 1A
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GO Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Tryptophan 2,3-dioxygenase Activity Protein Binding Oxidoreductase Activity Amino Acid Binding Oxygen Binding Heme Binding Identical Protein Binding Metal Ion Binding Dioxygenase Activity	Protein Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity Metal Ion Binding
	Biological Process	L-tryptophan Metabolic Process L-tryptophan Catabolic Process L-tryptophan Catabolic Process To Kynurenine L-tryptophan Catabolic Process To Acetyl-CoA Protein Homotetramerization Response To Nitroglycerin	Hippo Signaling
Pathways		Tryptophan catabolism	Signaling by Hippo
Drugs
Diseases
GWAS		Manganese levels ( 26025379) Speech perception in dyslexia ( 19786962)	Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		20 interacting genes: ASMTL DPM1 EIF4E KDM1A LMNA LNX1 MEOX2 MOB1A MOB3C NGB NMNAT1 NR1D1 PICK1 PM20D2 PRMT6 PSMA1 REL SDCBP SDCBP2 ZFYVE26	22 interacting genes: APP CCDC85B CMTM3 CREBBP FAM118A FAM9B GMEB2 HDAC6 IKZF4 KANK2 KXD1 LZTFL1 MST1 PCYT1A PTPN5 SEPTIN3 STRN3 TDO2 TMEM190 TRIM32 WASHC3 WEE2-AS1
Entrez ID		6999	55233
HPRD ID		01847	14727
Ensembl ID		ENSG00000151790	ENSG00000114978
Uniprot IDs		P48775	Q9H8S9
PDB IDs		4PW8 5TI9 5TIA 6A4I 6PYY 6PYZ 6UD5 6VBN 7LU7 7UI3 8QV7 8R5Q 8R5R 8VTQ 8VUG 8VZV 8W1H 8W2K 9AT2 9B17 9B1Q 9EZJ	1PI1 4J1V 4JIZ 5BRK 5BRM 5TWF 5TWG 5TWH 5XQZ 6MCP 6MCQ
Enriched GO Terms of Interacting Partners?			Regulation Of Intracellular Estrogen Receptor Signaling Pathway
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