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TDO2

Description tryptophan 2,3-dioxygenase
Image
GO Annotations Cellular Component
  • Cytosol
Molecular Function
  • Tryptophan 2,3-dioxygenase Activity
  • Protein Binding
  • Oxidoreductase Activity
  • Amino Acid Binding
  • Oxygen Binding
  • Heme Binding
  • Identical Protein Binding
  • Metal Ion Binding
  • Dioxygenase Activity
Biological Process
  • L-tryptophan Metabolic Process
  • L-tryptophan Catabolic Process
  • L-tryptophan Catabolic Process To Kynurenine
  • L-tryptophan Catabolic Process To Acetyl-CoA
  • Protein Homotetramerization
  • Response To Nitroglycerin
Pathways
  • Tryptophan catabolism
Drugs
Diseases
GWAS
  • Manganese levels ( 26025379)
  • Speech perception in dyslexia ( 19786962)
Interacting Genes 20 interacting genes: ASMTL DPM1 EIF4E KDM1A LMNA LNX1 MEOX2 MOB1A MOB3C NGB NMNAT1 NR1D1 PICK1 PM20D2 PRMT6 PSMA1 REL SDCBP SDCBP2 ZFYVE26
Entrez ID 6999
HPRD ID 01847
Ensembl ID ENSG00000151790
Uniprot IDs P48775
PDB IDs 4PW8 5TI9 5TIA 6A4I 6PYY 6PYZ 6UD5 6VBN 7LU7 7UI3 8QV7 8R5Q 8R5R 8VTQ 8VUG 8VZV 8W1H 8W2K 9AT2 9B17 9B1Q 9EZJ
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025