TCF12 and ARMC8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TCF12	ARMC8
Gene Name		transcription factor 12	armadillo repeat containing 8
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm RNA Polymerase II Transcription Factor Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Enhancer Binding BHLH Transcription Factor Binding Transcription Regulatory Region DNA Binding SMAD Binding Protein Heterodimerization Activity E-box Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Immune Response Muscle Organ Development Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		48 interactors: ARMC8 ASCL4 BMF C16orf45 C1orf109 C6orf165 CDKN2C CRCP CREBBP DGCR6 EDRF1 EP300 HAND1 HEXIM2 HOPX ID1 ID2 ID3 LYSMD1 MAPKBP1 MLLT6 MORN4 MSC NAGK NEUROG3 OLIG3 OSGIN1 PRSS23 PSMA1 PTF1A QARS RNASEL RUNX1T1 SOX10 SOX8 SPG21 SRI STAT5A STK16 TAF4 TAL2 TBP TCF23 TCF3 TRIM72 TSNAX TWIST2 VPS28	3 interactors: CTNNA1 TCF12 TNNT1
Entrez ID		6938	25852
HPRD ID		02725	09992
Ensembl ID		ENSG00000140262	ENSG00000114098
Uniprot IDs		B4E1W1 F5GY10 Q99081	B7Z637 Q8IUR7
PDB IDs		2KNH 4JOL
Enriched GO Terms of Interacting Partners?		Gene Expression Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Organ Development Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Developmental Process Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process System Development Transcription From RNA Polymerase II Promoter Biosynthetic Process Anatomical Structure Development Regulation Of DNA Binding Regulation Of Binding Negative Regulation Of DNA Binding Positive Regulation Of Transcription, DNA-templated Muscle Organ Development Central Nervous System Development Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Muscle Structure Development Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Binding Rhythmic Process Regulation Of Cellular Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Negative Regulation Of Integrin-mediated Signaling Pathway Cellular Response To Indole-3-methanol Slow-twitch Skeletal Muscle Fiber Contraction Gap Junction Assembly Negative Regulation Of Neuroblast Proliferation Muscle Structure Development Epithelial Cell-cell Adhesion Actin Filament-based Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Stem Cell Proliferation Regulation Of Integrin-mediated Signaling Pathway Regulation Of Neurogenesis Negative Regulation Of Muscle Contraction Axon Regeneration Skeletal Muscle Contraction Regulation Of Cell Development Positive Regulation Of Cell Differentiation Muscle Filament Sliding Actin-myosin Filament Sliding Positive Regulation Of Smoothened Signaling Pathway Neuron Projection Regeneration Negative Regulation Of Neural Precursor Cell Proliferation Regulation Of Neuroblast Proliferation Musculoskeletal Movement Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Actin-mediated Cell Contraction Response To Axon Injury Ovarian Follicle Development Apical Junction Assembly Actin Filament-based Movement Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Tagcloud ?		cadherin cascade cd91 connexin consistently crc drastically ectopic efficiently enhancement facilitated fibronectin gap hsp90alpha ikappabalpha ikkalpha ikks invasion junction knocked mesenchymal migration motifs outgrowths repressed rhsp90alpha secreted spherical spreading	a549 adjacent armadillo blotting cancerous canonical colony downregulated downregulation eukaryotes h1299 invasion knockdown lung metalloproteinase mmp mmp7 nsclc p120ctn promoted quantified repeat serve tissues tnm tumorigenesis upregulates wnt
Tagcloud (Difference) ?		cadherin cascade cd91 connexin consistently crc drastically ectopic efficiently enhancement facilitated fibronectin gap hsp90alpha ikappabalpha ikkalpha ikks junction knocked mesenchymal migration motifs outgrowths repressed rhsp90alpha secreted spherical spreading	a549 adjacent armadillo blotting cancerous canonical colony downregulated downregulation eukaryotes h1299 knockdown lung metalloproteinase mmp mmp7 nsclc p120ctn promoted quantified repeat serve tissues tnm tumorigenesis upregulates wnt
Tagcloud (Intersection) ?		invasion