ARMC8

Name	armadillo repeat containing 8
Structure
Interactors	10 interactors: CIB3 CTNNA1 GID8 PKP1 PKP2 STX6 TCF12 TNNT1 USP25 ZMYND12
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol GID Complex Specific Granule Lumen Tertiary Granule Lumen
	Molecular Function	Protein Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways	Neutrophil degranulation Regulation of pyruvate metabolism
GWAS	A body shape index ( 34021172 ) Mean spheric corpuscular volume ( 32888494 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Entrez ID	25852
HPRD ID	09992
Ensembl ID	ENSG00000114098
Uniprot IDs	B7Z637 Q8IUR7
PDB IDs	7NSC
GO Terms Enriched among Interactors ?	Intermediate Filament Binding Intermediate Filament Bundle Assembly Desmosome Assembly Desmosome Organization Cell-cell Junction Assembly Cell-cell Junction Organization Desmosome Adherens Junction Cell Junction Intercalated Disc Cell Junction Assembly Cornified Envelope Maintenance Of Protein Localization At Cell Tip Slow-twitch Skeletal Muscle Fiber Contraction Cadherin Binding Intermediate Filament Organization Desmosome Maintenance Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Anchoring Junction Negative Regulation Of Integrin-mediated Signaling Pathway Cytoskeleton Organization Positive Regulation Of Cap-dependent Translational Initiation Synaptic Vesicle To Endosome Fusion Negative Regulation Of Interleukin-17-mediated Signaling Pathway Cell Junction Organization Maintenance Of Animal Organ Identity Troponin T Binding Cell-cell Adhesion Cellular Response To Indole-3-methanol Transepithelial Water Transport Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication Ubiquitin-like Protein Peptidase Activity Response To Indole-3-methanol Positive Regulation Of Cytoplasmic Translational Initiation Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Interleukin-17A-mediated Signaling Pathway Apical Junction Assembly Gap Junction Assembly Zonula Adherens Nuclear Stress Granule Intermediate Filament Ameloblast Differentiation Regulation Of Muscle Contraction Cell Tip Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Response To Gonadotropin-releasing Hormone Troponin Complex Transition Between Fast And Slow Fiber Negative Regulation Of ERAD Pathway