GTF2A1 and GTF2E2

Number of citations of the paper that reports this interaction (PMID 9618479)
12

Data Source:
BioGRID (pull down, pull down)
HPRD (in vitro)

		GTF2A1	GTF2E2
Gene Name		general transcription factor IIA, 1, 19/37kDa	general transcription factor IIE, polypeptide 2, beta 34kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIIA Complex Cytoplasm	Nucleus Nucleoplasm Transcription Factor TFIIE Complex Cytoplasm
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding TBP-class Protein Binding Protein Heterodimerization Activity	DNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS			Cognitive performance ( 20125193)
Protein-Protein Interactions		18 interactors: BCL3 CREB1 CSNK2A1 CSNK2A2 GTF2A2 GTF2E1 GTF2E2 GTF2F1 HMGB1 NCOA6 NFYA TAF1 TAF4 TAF4B TASP1 TBP TBPL1 TRIP4	23 interactors: APP ATF7IP CCNH CDK7 ERCC3 ERCC6 FOS GTF2A1 GTF2B GTF2E1 GTF2F1 GTF2F2 GTF2H1 JUN KLF5 MCC MDM2 MNAT1 NUP62 SND1 SUPT16H TBP XPA
Entrez ID		2957	2961
HPRD ID		02748	01800
Ensembl ID		ENSG00000165417	ENSG00000197265
Uniprot IDs		P52655	P29084
PDB IDs		1NVP	1D8J 1D8K
Enriched GO Terms of Interacting Partners?		Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation DNA-templated Transcription, Elongation Transcription Initiation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Viral Process Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Polymerase II Transcriptional Preinitiation Complex Assembly Regulation Of Cellular Process Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Metabolic Process Rhythmic Process Intracellular Estrogen Receptor Signaling Pathway Regulation Of DNA-templated Transcription, Initiation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Secretory Granule Organization Regulation Of Proteasomal Protein Catabolic Process Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Apoptotic Cell Clearance	DNA-templated Transcription, Elongation Transcription Elongation From RNA Polymerase II Promoter Viral Process Positive Regulation Of Viral Transcription Transcription Initiation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Regulation Of Viral Transcription Positive Regulation Of Viral Process DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase I Promoter Transcription, DNA-templated Positive Regulation Of Gene Expression RNA Biosynthetic Process 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter 7-methylguanosine RNA Capping RNA Metabolic Process Nucleotide-excision Repair, DNA Damage Removal Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Viral Process Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Termination Of RNA Polymerase I Transcription Regulation Of RNA Metabolic Process Transcription Initiation From RNA Polymerase I Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Macromolecule Biosynthetic Process Nucleotide-excision Repair Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression, Epigenetic DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Metabolic Process Biosynthetic Process DNA Catabolic Process Regulation Of Metabolic Process MRNA Processing Negative Regulation Of Gene Expression
Tagcloud ?			avenues bioinformatics bl canonical conferring dhx8 disrupted dnaja1 galactosidase hap1 insertional kalrn lytic mechanistic mutagenesis participate queried replication screens share tat throughput tzm uba3 ube2e3 utilizing viable vmp1
Tagcloud (Difference) ?			avenues bioinformatics bl canonical conferring dhx8 disrupted dnaja1 galactosidase hap1 insertional kalrn lytic mechanistic mutagenesis participate queried replication screens share tat throughput tzm uba3 ube2e3 utilizing viable vmp1
Tagcloud (Intersection) ?