GTF2A1 and TASP1

Number of citations of the paper that reports this interaction (PubMedID 16537915)
29

Data Source:
HPRD (in vitro, in vivo)

		GTF2A1	TASP1
Description		general transcription factor IIA subunit 1	taspase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIA Complex Cytoplasm Cytosol Transcription Preinitiation Complex	Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Threonine-type Endopeptidase Activity Peptidase Activity Hydrolase Activity Identical Protein Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	Proteolysis Positive Regulation Of DNA-templated Transcription Protein Maturation
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance Estrogen-dependent gene expression	Formation of WDR5-containing histone-modifying complexes Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Neutrophil count ( 32888494) Night sleep phenotypes ( 27126917) Thyroid stimulating hormone levels ( 32769997) White blood cell count ( 32888494)	Chin dimples ( 27182965) Daytime sleep phenotypes ( 27126917) Night sleep phenotypes ( 27126917)
Interacting Genes		26 interacting genes: BCL3 BIRC7 CREB1 CSNK2A1 CSNK2A2 GTF2A2 GTF2E1 GTF2E2 GTF2F1 HMGB1 NCOA6 NFYA PRR20A PRR20B PRR20C PRR20D PRR20E PSMC6 SP4 TAF1 TAF4 TAF4B TASP1 TBP TBPL1 TRIP4	4 interacting genes: APP FBXL17 GTF2A1 KMT2A
Entrez ID		2957	55617
HPRD ID		02748	07460
Ensembl ID		ENSG00000165417	ENSG00000089123
Uniprot IDs		P52655	Q9H6P5
PDB IDs		1NVP 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5M4S 6MZM 6O9L 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGI 7EGJ 7LBM 7NVR 7NVS 7NVT 7NVU 7NVY 7NVZ 7NW0 7ZWC 7ZWD 7ZX7 7ZX8 7ZXE 8BVW 8BYQ 8BZ1 8GXQ 8GXS 8S51 8S52 8S5N 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS	2A8I 2A8J 2A8L 2A8M 6UGK 6VIN
Enriched GO Terms of Interacting Partners?		RNA Polymerase II General Transcription Initiation Factor Activity DNA-templated Transcription Initiation Transcription Factor TFIID Complex Transcription Initiation At RNA Polymerase II Promoter Transcription By RNA Polymerase II Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation DNA-templated Transcription Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Nucleobase-containing Compound Biosynthetic Process RNA Polymerase II General Transcription Initiation Factor Binding RNA Metabolic Process Nucleic Acid Metabolic Process Macromolecule Biosynthetic Process MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly RNA Polymerase II-specific DNA-binding Transcription Factor Binding MRNA Transcription Transcription Factor TFIIA Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Nucleobase-containing Compound Metabolic Process Nucleoplasm Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process Transcription Factor TFIIE Complex Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Transcription By RNA Polymerase II Protein Kinase CK2 Complex Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Protein-DNA Complex Assembly Nucleus Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Aryl Hydrocarbon Receptor Binding Male Germ Cell Nucleus Regulation Of Gene Expression	Acetylcholine Receptor Activator Activity Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex PTB Domain Binding Regulation Of Neuronal Synaptic Plasticity Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Associative Learning Visual Behavior Regulation Of Response To Calcium Ion Cell Activation Involved In Immune Response Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Visual Learning Growth Cone Filopodium Learning Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of DNA Methylation-dependent Heterochromatin Formation Protein-cysteine Methyltransferase Activity ADP-ribosylglutamate Hydrolase Activity Peptidyl-glutamate ADP-deribosylation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Synaptic Plasticity Axon Midline Choice Point Recognition Hemopoiesis Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Transcription Factor TFIIA Complex Negative Regulation Of Heterochromatin Formation O-acetyl-ADP-ribose Deacetylase Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Macromolecule Metabolic Process Protein De-ADP-ribosylation Axon Choice Point Recognition
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