TAF4B and TAF12

Number of citations of the paper that reports this interaction (PMID 15601843)
24

Data Source:
BioGRID (pull down)

		TAF4B	TAF12
Gene Name		TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Nucleolus Cytoplasm	PCAF Complex Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Heterodimerization Activity NF-kappaB Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Spermatogenesis Gene Expression Viral Process Oogenesis	Chromatin Organization DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Histone H3 Acetylation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Nucleic Acid-templated Transcription
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Chromatin organization HIV Infection HATs acetylate histones RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation Chromatin modifying enzymes RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS		Rhegmatogenous retinal detachment ( 23585552) Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-Protein Interactions		5 interactors: GTF2A1 HIST3H3 RELA TAF1 TAF12	22 interactors: ATF7 CPSF1 HIST3H3 NFYA NFYB NFYC PRKAR2B TAF1 TAF10 TAF11 TAF15 TAF1A TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I
Entrez ID		6875	6883
HPRD ID		19270	15981
Ensembl ID		ENSG00000141384	ENSG00000120656
Uniprot IDs		J3KTH2 Q92750	Q16514
PDB IDs			1H3O
Enriched GO Terms of Interacting Partners?		Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Viral Process Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Acetaldehyde Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Nucleobase-containing Compound Metabolic Process Protein Acetylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Schwann Cell Differentiation Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Regulation Of Schwann Cell Differentiation RNA Polymerase II Transcriptional Preinitiation Complex Assembly Nitrogen Compound Metabolic Process Chromosome Organization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Cobalamin Peptidyl-lysine Modification Positive Regulation Of MiRNA Metabolic Process Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway RNA Metabolic Process Cellular Response To Nicotine Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Gene Expression Regulation Of MiRNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Protein Catabolic Process Macromolecule Biosynthetic Process Histone Modification Regulation Of Interleukin-12 Biosynthetic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Response To Muramyl Dipeptide Response To UV-B Membrane Protein Intracellular Domain Proteolysis Positive Regulation Of DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Regulation Of DNA-templated Transcription, Initiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway	DNA-templated Transcription, Elongation Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Initiation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Viral Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Peptidyl-lysine Modification Protein Acetylation Positive Regulation Of Metabolic Process Metabolic Process Histone H3 Acetylation Histone Modification DNA-templated Transcription, Termination Regulation Of Cellular Process Chromatin Silencing At RDNA Regulation Of Transcription From RNA Polymerase II Promoter Peptidyl-amino Acid Modification Chromatin Modification Chromosome Organization Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter
Tagcloud ?		cascades chemoresistance cofactor compose d2 dedifferentiation deleted deregulation directs drive execute expand granulosa helps hgsc initiator outline ovarian ovary paralog pluripotent serous strikingly taf2 taf9 tafs tata tfiid	adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf4 tafs tfiid
Tagcloud (Difference) ?		cascades chemoresistance cofactor compose d2 dedifferentiation deleted deregulation directs drive execute expand granulosa helps hgsc initiator outline ovarian ovary paralog pluripotent serous strikingly taf2 taf9 tata	adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset
Tagcloud (Intersection) ?		taf4 tafs tfiid