HLTF and SULT1C2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		HLTF	SULT1C2
Description		helicase like transcription factor	sulfotransferase family 1C member 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Membrane Nuclear Matrix Nuclear Replication Fork RNA Polymerase II Transcription Regulator Complex	Cytoplasm Mitochondrion Lysosome Cytosol
	Molecular Function	Nucleotide Binding Nucleic Acid Binding DNA Binding Single-stranded DNA Binding RNA Binding Catalytic Activity Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Zinc Ion Binding DNA Translocase Activity Transferase Activity Hydrolase Activity Hydrolase Activity, Acting On Acid Anhydrides, In Phosphorus-containing Anhydrides Ubiquitin Protein Ligase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Aryl Sulfotransferase Activity Protein Binding Sulfotransferase Activity Transferase Activity Cholesterol Sulfotransferase Activity
	Biological Process	Protein Polyubiquitination DNA Repair Chromatin Organization DNA Damage Response Protein Ubiquitination MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Neurogenesis Replication Fork Reversal	Amine Metabolic Process Sulfation
Pathways		E3 ubiquitin ligases ubiquitinate target proteins	Cytosolic sulfonation of small molecules
Drugs
Diseases
GWAS			Aluminium levels ( 26025379) Eyebrow thickness ( 26926045) Gut microbiota (functional units) ( 27694959) Parkinson's disease progression (composite) ( 33111402)
Interacting Genes		14 interacting genes: CDK9 CEBPA DCAF1 EEF1G EWSR1 HSPA8 SP1 SP3 SULT1C2 UBC UBE2A UBE2V2 UBE2Z WBP4	6 interacting genes: ACD HLTF POT1 RASGRP3 TERF1 TINF2
Entrez ID		6596	6819
HPRD ID		04461	03858
Ensembl ID		ENSG00000071794	ENSG00000198203
Uniprot IDs		A0A0C4DGA6 A8K5B6 Q05BZ6 Q14527	O00338
PDB IDs		2MZN 4HRE 4HRH 4S0N 4XZF 4XZG 5BNH 5K5F 6KCS	3BFX
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Host-mediated Perturbation Of Viral Transcription Host-mediated Activation Of Viral Transcription Granulocyte Differentiation Embryonic Placenta Development Protein Ubiquitination Protein Modification By Small Protein Conjugation Host-mediated Activation Of Viral Process Post-translational Protein Modification Postreplication Repair Ubiquitin Conjugating Enzyme Activity Nucleic Acid Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Protein Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Chaperone-mediated Autophagy Translocation Complex Disassembly Positive Regulation Of Hydrogen Sulfide Biosynthetic Process Protein-DNA Complex Cellular Response To Wortmannin Histone H2AT120 Kinase Activity Cell Competition In A Multicellular Organism Cellular Response To Stress Macromolecule Metabolic Process Modification-dependent Protein Catabolic Process Macromolecule Catabolic Process Protein Modification Process Transcription Cis-regulatory Region Binding Transcription Repressor Complex P-TEFb Complex Response To Vitamin B2 C/EBP Complex Lumenal Side Of Lysosomal Membrane Response To Wortmannin Cholesterol Sulfotransferase Activity Error-free Postreplication DNA Repair Host-mediated Perturbation Of Viral Process Ubiquitin Protein Ligase Binding Proteolysis Involved In Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Mononuclear Cell Differentiation DNA Metabolic Process Positive Regulation Of Protein Localization To Chromatin CHOP-C/EBP Complex Regulation Of Protein Import UBC13-MMS2 Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process ATP Binding Regulation Of Nucleobase-containing Compound Metabolic Process	Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Telomere Assembly Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Regulation Of DNA Biosynthetic Process Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Telomere Maintenance Via Telomerase Telomere Organization Negative Regulation Of DNA Metabolic Process RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Chromosome, Telomeric Region Regulation Of Chromosome Organization DNA Metabolic Process Positive Regulation Of DNA Metabolic Process Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Chromosome Organization DNA Biosynthetic Process Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Protein Localization To Chromosome, Telomeric Region Regulation Of DNA Metabolic Process Positive Regulation Of Organelle Organization Chromosome Negative Regulation Of Cellular Component Organization Nucleobase-containing Compound Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process DNA Binding Nuclear Body Positive Regulation Of Cellular Component Organization Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?