SNRPD3 and STRAP

Number of citations of the paper that reports this interaction (PubMedID 15848170)
0

Data Source:
HPRD (in vitro)

		SNRPD3	STRAP
Description		small nuclear ribonucleoprotein D3 polypeptide	serine/threonine kinase receptor associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Commitment Complex Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U2-type Spliceosomal Complex U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Telomerase Holoenzyme Complex Cytoplasm Cytosol Nuclear Body Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Ribonucleoprotein Complex	Nucleus Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex
	Molecular Function	RNA Binding Protein Binding Enzyme Binding Telomerase RNA Binding Histone Pre-mRNA DCP Binding U7 SnRNA Binding	RNA Binding MRNA Binding Signaling Receptor Binding Protein Binding U2 SnRNP Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing Protein Methylation RNA Splicing 7-methylguanosine Cap Hypermethylation U2-type Prespliceosome Assembly	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Protein-RNA Complex Assembly Neuron Differentiation Maintenance Of Gastrointestinal Epithelium Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Pathways		SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs SARS-CoV-2 modulates host translation machinery	Downregulation of TGF-beta receptor signaling Downregulation of TGF-beta receptor signaling Positive Regulation of CDH1 Gene Transcription
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Gamma glutamyl transferase levels ( 32084209)
Interacting Genes		28 interacting genes: CASP8 CEBPA CRY1 DDX20 FNDC3B GEMIN2 GEMIN5 GEMIN6 GEMIN7 IL12RB1 IL7R LSM3 LSM7 NR1I3 NTAQ1 PRMT5 RBL1 SMN1 SMN2 SNRPB SNRPE SNRPG SREK1 STRAP STXBP2 STXBP3 TRDMT1 WDR77	31 interacting genes: ANXA1 CEBPA CHEK2 FOXP1 GEMIN6 GEMIN7 MAP1B MTRES1 NEIL3 NXF1 PBLD PDPK1 PTEN RN7SL1 RNU1-1 RNU2-1 SMAD2 SMAD3 SMAD6 SMAD7 SMN1 SMURF1 SNRPB SNRPD2 SNRPD3 SNRPE SUMO2 SUMO4 SZRD1 TGFBR1 TGFBR2
Entrez ID		6634	11171
HPRD ID		03039	05816
Ensembl ID		ENSG00000100028	ENSG00000023734
Uniprot IDs		P62318	Q9Y3F4
PDB IDs		1D3B 3CW1 3JCR 3PGW 3VRI 4PJO 4WZJ 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6V4X 6Y53 6Y5Q 7A5P 7ABG 7ABI 7B0Y 7DVQ 7EVO 7QTT 7VPX 7W59 7W5A 7W5B 8C6J 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8Q7Q 8Q7V 8Q7W 8Q7X 8Q91 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8R7N 8RC0 8RM5 8RO2 8Y6O 8Y7E 9FMD 9GBW 9GC0 9GCL
Enriched GO Terms of Interacting Partners?		SMN-Sm Protein Complex Spliceosomal SnRNP Assembly SMN Complex Protein-RNA Complex Assembly Gemini Of Cajal Bodies RNA Splicing RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process RNA Processing Spliceosomal Complex Assembly RNA Metabolic Process Methylosome MRNA Splicing, Via Spliceosome Nucleic Acid Metabolic Process U4/U6 X U5 Tri-snRNP Complex Spliceosomal Complex U2-type Precatalytic Spliceosome RNA Binding Protein-containing Complex Assembly Nucleobase-containing Compound Metabolic Process Nucleoplasm U12-type Spliceosomal Complex Protein-containing Complex Organization U7 SnRNP 7-methylguanosine Cap Hypermethylation Catalytic Step 2 Spliceosome Macromolecule Metabolic Process U4 SnRNP Cellular Component Assembly Macromolecule Methylation Nucleus Nuclear Body Small Nuclear Ribonucleoprotein Complex Cytosol U2 SnRNP Binding U2-type Prespliceosome DNA-templated Transcription Termination U1 SnRNP Precatalytic Spliceosome U5 SnRNP RNA Methylation Tertiary Granule U2-type Prespliceosome Assembly U2 SnRNP U2-type Spliceosomal Complex Presynaptic Dense Core Vesicle Exocytosis U2-type Catalytic Step 2 Spliceosome Methylation Lsm1-7-Pat1 Complex	SMN-Sm Protein Complex I-SMAD Binding Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly Heteromeric SMAD Protein Complex 7-methylguanosine Cap Hypermethylation SMAD Protein Signal Transduction U2 SnRNP Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Protein-RNA Complex Assembly Type I Transforming Growth Factor Beta Receptor Binding U4 SnRNP Response To Growth Factor Methylosome Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Small Nuclear Ribonucleoprotein Complex Cellular Response To Growth Factor Stimulus Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway U1 SnRNP Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway U5 SnRNP Regulation Of Epithelial To Mesenchymal Transition RNA Splicing, Via Transesterification Reactions Activin Receptor Binding U2-type Prespliceosome Assembly U12-type Spliceosomal Complex PICln-Sm Protein Complex Nucleoplasm R-SMAD Binding Regulation Of SMAD Protein Signal Transduction Trophoblast Cell Migration U7 SnRNP U2-type Spliceosomal Complex Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway U2-type Catalytic Step 2 Spliceosome U4/U6 X U5 Tri-snRNP Complex Ureteric Bud Development SMN Complex Ubiquitin Protein Ligase Binding Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Ossification Co-SMAD Binding Gemini Of Cajal Bodies Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MRNA Splicing, Via Spliceosome Mesonephric Tubule Development Mesonephric Epithelium Development SMAD Binding
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