CD79A and PIGR

Number of citations of the paper that reports this interaction (PMID 10540352)
3

Data Source:
HPRD (in vivo)

		CD79A	PIGR
Gene Name		CD79a molecule, immunoglobulin-associated alpha	polymeric immunoglobulin receptor
Image
Gene Ontology Annotations	Cellular Component	Multivesicular Body Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane B Cell Receptor Complex Membrane Raft	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity	Polymeric Immunoglobulin Receptor Activity
	Biological Process	B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Retina Homeostasis Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Epidermal Growth Factor Receptor Signaling Pathway Fc Receptor Signaling Pathway Receptor Clustering
Pathways		Signaling by the B Cell Receptor (BCR) Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Adaptive Immune System
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		17 interactors: BLK BLNK CD19 CD5 CD79B FANCA FATE1 FCAR FYN HCLS1 IGHM IGJ LCK LYN PIGR PTPN6 SYK	4 interactors: AP1M1 CCL5 CD79A RAB3B
Entrez ID		973	5284
HPRD ID		00203	01436
Ensembl ID		ENSG00000105369	ENSG00000162896
Uniprot IDs		P11912	P01833
PDB IDs		1CV9	1XED 2OCW 3CHN 3CM9
Enriched GO Terms of Interacting Partners?		B Cell Receptor Signaling Pathway Immune System Process Antigen Receptor-mediated Signaling Pathway Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Immune System Process Regulation Of Immune System Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Regulation Of Immune Response T Cell Costimulation Enzyme Linked Receptor Protein Signaling Pathway Defense Response Positive Regulation Of Immune Response Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Fc Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Regulation Of T Cell Activation Positive Regulation Of Cell Activation Response To Stimulus Hemopoiesis Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Cell Activation Regulation Of Lymphocyte Activation Platelet Activation Immune System Development Protein Autophosphorylation Regulation Of Peptidyl-tyrosine Phosphorylation Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Regulation Of Cell Activation Leukocyte Activation Intracellular Signal Transduction Cellular Response To Peptide Hormone Stimulus Response To Stress Cellular Response To Peptide Homotypic Cell-cell Adhesion Regulation Of Cell Proliferation Regulation Of Cell Adhesion Leukocyte Differentiation Regulation Of Cellular Localization Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein	Immune System Process Regulation Of Vesicle Size Positive Regulation Of Ion Transport Peptidyl-cysteine Methylation Negative Regulation Of Macrophage Apoptotic Process Regulation Of Immune System Process Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Natural Killer Cell Chemotaxis Negative Regulation Of Chemokine-mediated Signaling Pathway Antigen Processing And Presentation Vesicle-mediated Transport Positive Regulation Of Activation Of JAK2 Kinase Activity Positive Regulation Of Activation Of Janus Kinase Activity Exocytosis Positive Regulation Of Macrophage Chemotaxis Pigment Granule Maturation Endosome To Melanosome Transport Eosinophil Chemotaxis Eosinophil Migration Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of T Cell Chemotaxis Regulation Of Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Synaptic Transmission, Dopaminergic Cellular Pigment Accumulation Negative Regulation By Host Of Viral Transcription Positive Regulation Of Monocyte Chemotaxis Regulation Of Chronic Inflammatory Response Establishment Of Localization In Cell Regulation Of Macrophage Chemotaxis Regulation Of Monocyte Chemotaxis Positive Regulation Of Translational Initiation Dendritic Cell Chemotaxis Leukocyte Activation Activation Of Phospholipase D Activity Regulation Of Neurotransmitter Uptake Positive Regulation Of T Cell Apoptotic Process Monocyte Chemotaxis Regulation Of Macrophage Apoptotic Process Secretion By Cell Positive Regulation Of Cell Adhesion Mediated By Integrin Macrophage Chemotaxis Extracellular Negative Regulation Of Signal Transduction Positive Regulation Of T Cell Migration Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Myeloid Cell Apoptotic Process Positive Regulation Of Lymphocyte Apoptotic Process Regulation Of T Cell Migration Negative Regulation Of Viral Transcription Melanosome Organization
Tagcloud ?		abdomen axillae bence cd138 cd20 cd56 dermis disappearing emp enlarged extramedullar fig immunohistological inguinal jones microglobulin monotypic painless pcp pcps plasmacytoid plasmacytoma pointed reappeared runs subcutis temporarily vincristine	adenoids belonging defense degranulation destructive dimers eosinophils extravasation glandular helper iga ige immunopathology leukocytes migrate mucosa penetrating perhaps piga polymers priming reaches secretions secretory th2 tonsils transported unsuccessful
Tagcloud (Difference) ?		abdomen axillae bence cd138 cd20 cd56 dermis disappearing emp enlarged extramedullar fig immunohistological inguinal jones microglobulin monotypic painless pcp pcps plasmacytoid plasmacytoma pointed reappeared runs subcutis temporarily vincristine	adenoids belonging defense degranulation destructive dimers eosinophils extravasation glandular helper iga ige immunopathology leukocytes migrate mucosa penetrating perhaps piga polymers priming reaches secretions secretory th2 tonsils transported unsuccessful
Tagcloud (Intersection) ?