NXT1 and DDOST

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		NXT1	DDOST
Description		nuclear transport factor 2 like export factor 1	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
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GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Speck Nuclear RNA Export Factor Complex Nuclear Pore Central Transport Channel	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Oligosaccharyltransferase Complex Membrane Azurophil Granule Membrane Intracellular Membrane-bounded Organelle Oligosaccharyltransferase Complex A Oligosaccharyltransferase Complex B
	Molecular Function	Protein Binding Small GTPase Binding	Protein Binding Enzyme Activator Activity
	Biological Process	RNA Export From Nucleus MRNA Export From Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Protein Transport Poly(A)+ MRNA Export From Nucleus	Protein Glycosylation Protein N-linked Glycosylation Protein N-linked Glycosylation Via Asparagine Regulation Of Protein Stability Response To Cytokine T Cell Activation
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript	SRP-dependent cotranslational protein targeting to membrane Asparagine N-linked glycosylation Neutrophil degranulation Advanced glycosylation endproduct receptor signaling Maturation of spike protein Regulation of CDH1 posttranslational processing and trafficking to plasma membrane PD-L1(CD274) glycosylation and translocation to plasma membrane
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Proportion of activated microglia (inferior temporal cortex) ( 30679421)
Interacting Genes		8 interacting genes: DDOST FBXO16 NXF1 NXF2 NXF3 RAN STAU1 XPO1	7 interacting genes: ISG15 LTB4R2 MAPK6 NXT1 PTEN SRSF11 STING1
Entrez ID		29107	1650
HPRD ID		16159	03728
Ensembl ID		ENSG00000132661	ENSG00000244038
Uniprot IDs		Q9UKK6	P39656
PDB IDs		1JKG 1JN5 4WYK 6E5U	6S7O 6S7T 8B6L 8PN9
Enriched GO Terms of Interacting Partners?		RNA Export From Nucleus Nuclear Export RNA Transport Nuclear RNA Export Factor Complex Nucleobase-containing Compound Transport MRNA Export From Nucleus Nuclear Transport Nucleocytoplasmic Transport Poly(A)+ MRNA Export From Nucleus MRNA Transport Intracellular Transport Ribosomal Large Subunit Export From Nucleus Ribosomal Small Subunit Export From Nucleus Nuclear Export Signal Receptor Activity Cellular Localization RNA Binding Ribosomal Subunit Export From Nucleus Establishment Of Localization In Cell Protein Export From Nucleus Nuclear Envelope Nuclear Pore RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Cytoplasmic Stress Granule Cellular Response To Triglyceride Regulation Of Nucleocytoplasmic Transport Anterograde Dendritic Transport Of Messenger Ribonucleoprotein Complex RNA Import Into Nucleus Positive Regulation By Virus Of Viral Protein Levels In Host Cell Response To Triglyceride Nucleic Acid Binding Regulation Of Intracellular Protein Transport LncRNA-mediated Post-transcriptional Gene Silencing Annulate Lamellae Cellular Response To Salt Protein Localization To Nucleus Oligosaccharyltransferase Complex B Germ Cell Development Oligosaccharyltransferase Complex A Pre-miRNA Binding Protein-containing Complex Importin-alpha Family Protein Binding Protein Domain Specific Binding Cellular Response To Mineralocorticoid Stimulus Protein Localization To Nucleolus Intracellular Protein Localization Anterograde Dendritic Transport Intracellular MRNA Localization Nuclear Inclusion Body	Nucleoplasm Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Interferon-beta Production Septin Cytoskeleton Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Positive Regulation Of Type I Interferon Production Regulation Of Interferon-beta Production Leukotriene B4 Receptor Activity Cyclic-di-GMP Binding STING Complex 2',3'-cyclic GMP-AMP Binding Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Regulation Of Type I Interferon Production Leukotriene Receptor Activity Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Positive Regulation Of Protein Oligomerization Leukotriene Signaling Pathway
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