NXT1 and NXF2

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		NXT1	NXF2
Description		nuclear transport factor 2 like export factor 1	nuclear RNA export factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Speck Nuclear RNA Export Factor Complex Nuclear Pore Central Transport Channel	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear RNA Export Factor Complex
	Molecular Function	Protein Binding Small GTPase Binding	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	RNA Export From Nucleus MRNA Export From Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Protein Transport Poly(A)+ MRNA Export From Nucleus	MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus RNA Transport MRNA Transport
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript	Transport of Mature mRNA derived from an Intron-Containing Transcript
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		8 interacting genes: DDOST FBXO16 NXF1 NXF2 NXF3 RAN STAU1 XPO1	12 interacting genes: ALG13 APEX1 APP HNRNPUL1 MAP1A MAP1B NUP153 NUP214 NUP62 NXF1 NXT1 NXT2
Entrez ID		29107	56001
HPRD ID		16159	02260
Ensembl ID		ENSG00000132661	ENSG00000269405
Uniprot IDs		Q9UKK6	Q9GZY0
PDB IDs		1JKG 1JN5 4WYK 6E5U
Enriched GO Terms of Interacting Partners?		RNA Export From Nucleus Nuclear Export RNA Transport Nuclear RNA Export Factor Complex Nucleobase-containing Compound Transport MRNA Export From Nucleus Nuclear Transport Nucleocytoplasmic Transport Poly(A)+ MRNA Export From Nucleus MRNA Transport Intracellular Transport Ribosomal Large Subunit Export From Nucleus Ribosomal Small Subunit Export From Nucleus Nuclear Export Signal Receptor Activity Cellular Localization RNA Binding Ribosomal Subunit Export From Nucleus Establishment Of Localization In Cell Protein Export From Nucleus Nuclear Envelope Nuclear Pore RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Cytoplasmic Stress Granule Cellular Response To Triglyceride Regulation Of Nucleocytoplasmic Transport Anterograde Dendritic Transport Of Messenger Ribonucleoprotein Complex RNA Import Into Nucleus Positive Regulation By Virus Of Viral Protein Levels In Host Cell Response To Triglyceride Nucleic Acid Binding Regulation Of Intracellular Protein Transport LncRNA-mediated Post-transcriptional Gene Silencing Annulate Lamellae Cellular Response To Salt Protein Localization To Nucleus Oligosaccharyltransferase Complex B Germ Cell Development Oligosaccharyltransferase Complex A Pre-miRNA Binding Protein-containing Complex Importin-alpha Family Protein Binding Protein Domain Specific Binding Cellular Response To Mineralocorticoid Stimulus Protein Localization To Nucleolus Intracellular Protein Localization Anterograde Dendritic Transport Intracellular MRNA Localization Nuclear Inclusion Body	RNA Export From Nucleus MRNA Transport Nuclear Export RNA Transport Nuclear Pore Nucleobase-containing Compound Transport Nuclear Pore Central Transport Channel Intracellular Transport Nuclear Transport Nucleocytoplasmic Transport Nuclear RNA Export Factor Complex Cellular Localization Establishment Of Localization In Cell MRNA Export From Nucleus Structural Constituent Of Nuclear Pore Poly(A)+ MRNA Export From Nucleus PTB Domain Binding Protein Transport Dendrite Development Establishment Of Protein Localization Nuclear Envelope Intracellular Protein Transport Nuclear Inclusion Body Neuron Projection Maintenance Intracellular Protein Localization Protein Import Into Nucleus Import Into Nucleus Nuclear Localization Sequence Binding Axonogenesis Amyloid Fibril Formation Regulation Of Microtubule Cytoskeleton Organization Transport Along Microtubule Protein Localization To Nucleus Protein Export From Nucleus Cytoskeleton-dependent Intracellular Transport Regulation Of Microtubule Depolymerization Microtubule Associated Complex Regulation Of Synaptic Plasticity Dendritic Shaft Neuron Projection Organization Microtubule-based Transport Positive Regulation Of Gene Expression, Epigenetic Phosphodiesterase Activity, Acting On 3'-phosphoglycolate-terminated DNA Strands Class II DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity Telomere Maintenance Via Base-excision Repair Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway
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