ZNF641 and SQLE

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ZNF641	SQLE
Gene Name		zinc finger protein 641	squalene epoxidase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Metal Ion Binding	Squalene Monooxygenase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter	Cholesterol Biosynthetic Process Cellular Aromatic Compound Metabolic Process Response To Organic Substance Sterol Biosynthetic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Generic Transcription Pathway	Regulation of cholesterol biosynthesis by SREBP (SREBF) Cholesterol biosynthesis Metabolism of lipids and lipoproteins Activation of gene expression by SREBF (SREBP)
Drugs			Naftifine Terbinafine Butenafine Ellagic Acid
Diseases
GWAS
Protein-Protein Interactions		2 interactors: KDM1A SQLE	3 interactors: ALDOC CREB3 ZNF641
Entrez ID		121274	6713
HPRD ID		08711	11802
Ensembl ID		ENSG00000167528	ENSG00000104549
Uniprot IDs		Q96N77	Q14534 Q5HYI4 Q9UNR6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Granulocyte Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Histone H3-K4 Methylation Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hormone Biosynthetic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Cholesterol Biosynthetic Process Histone Lysine Demethylation Regulation Of Hormone Metabolic Process Histone Demethylation Regulation Of Erythrocyte Differentiation Protein Demethylation Sterol Biosynthetic Process Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of DNA Binding Oxidation-reduction Process Regulation Of Histone Methylation Positive Regulation Of Neural Precursor Cell Proliferation Pituitary Gland Development Negative Regulation Of Protein Binding Demethylation Positive Regulation Of Stem Cell Proliferation Positive Regulation Of Myeloid Cell Differentiation Regulation Of DNA Binding Negative Regulation Of Chromosome Organization Diencephalon Development Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Binding Regulation Of Neural Precursor Cell Proliferation Cholesterol Metabolic Process Regulation Of Stem Cell Proliferation Myeloid Leukocyte Differentiation Steroid Biosynthetic Process Regulation Of Embryonic Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Release From Viral Latency Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of Deacetylase Activity Establishment Of Viral Latency Positive Regulation Of Monocyte Chemotaxis Protein Heterotetramerization Regulation Of Monocyte Chemotaxis Positive Regulation Of Defense Response To Virus By Host Induction Of Positive Chemotaxis Fructose Metabolic Process Cytoplasmic Sequestering Of Transcription Factor Cytoplasmic Sequestering Of Protein Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Defense Response To Virus By Host Positive Regulation Of Positive Chemotaxis Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus
Tagcloud ?			activin alp c1orf19 cdm chsy cobblestone cryab csrp1 dusp6 epas1 foetal gfpt2 grem1 hmgcs1 immunocytochemistry intermediary morphogenetic mt1x osr2 postn ppl rabgap1 sc4mol sox sox15 srgn stro therein wif1
Tagcloud (Difference) ?			activin alp c1orf19 cdm chsy cobblestone cryab csrp1 dusp6 epas1 foetal gfpt2 grem1 hmgcs1 immunocytochemistry intermediary morphogenetic mt1x osr2 postn ppl rabgap1 sc4mol sox sox15 srgn stro therein wif1
Tagcloud (Intersection) ?