ZNF641 and DTX2

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		ZNF641	DTX2
Description		zinc finger protein 641	deltex E3 ubiquitin ligase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol	Nucleus Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Notch Signaling Pathway Protein Ubiquitination
Pathways		Generic Transcription Pathway	Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462 31152163) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Red blood cell count ( 27863252)
Interacting Genes		8 interacting genes: APP DTX2 KDM1A LMO1 LMO2 LMO3 SCNM1 SQLE	135 interacting genes: ABHD11 ABHD16A ACTMAP ALKBH4 ANAPC11 ANTKMT ARID5A ARMC7 ARNT2 BCL2L11 BICRAL BOLA2-SMG1P6 C10orf55 C1orf94 C22orf39 CCDC57 CFAP68 CIMIP1 CLPP COA6 COQ8A DAZAP2 DOK3 DTX1 DTX3 ECM1 ECSIT EIF4ENIF1 EIF4G1 EYA2 FAM168A FCRL4 FHL2 FHL5 FOXI1 FTO GLYCTK GOLGA2 H3C1 HDC HGS HLX HOXA1 HOXB2 HOXD12 HPCA HPCAL1 HPCAL4 HSFY1 HSFY2 IKZF3 KANK2 KLC3 KLHDC7B KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP19-1 KRTAP19-6 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP7-1 KRTAP8-1 LASP1 LNX1 LRP2BP MBD3L1 MDC1 MED19 MSS51 MVP MXRA8 NCALD NCS1 NHLRC4 NIF3L1 NME4 NOTCH1 OIP5 PARP1 PARP10 PAX5 PLEKHF2 PLEKHG4 PLSCR1 POGZ PRR32 PRR34 PSMB4 QARS1 RBM11 RBPMS RFX6 RHOXF2 RIMBP3 RUNX1 RUNX2 RUNX3 RUSC1 SAXO4 SEC22A SEC23A SEC23B SEPSECS SLC67A1-AS SOHLH1 SPAG8 STX12 SUMO1 TBX15 TEKT5 TENT2 TMEM42 TRIB3 TRIM35 TRIM54 TRIP13 TRIP6 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBQLN4 USP54 VGLL3 VSNL1 ZNF34 ZNF503 ZNF620 ZNF641 ZNF764 ZNF774 ZNF85
Entrez ID		121274	113878
HPRD ID		08711	16841
Ensembl ID		ENSG00000167528	ENSG00000091073
Uniprot IDs		Q96N77	Q86UW9
PDB IDs			6IR0 6Y22 6Y2X 6Y3J
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Binding Transcription Coactivator Activity Neuron Maturation Positive Regulation Of Transcription By RNA Polymerase II Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of RNA Biosynthetic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Positive Regulation Of DNA-templated Transcription Squalene Monooxygenase Activity Flavin Adenine Dinucleotide Binding Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Enzyme Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of RNA Metabolic Process Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Nucleobase-containing Compound Metabolic Process Lipoprotein Particle Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Regulation Of T Cell Homeostatic Proliferation Response To Biphenyl Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Metal Ion Binding Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Protein Demethylase Activity Response To Purine-containing Compound Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Amyloid Fibril Formation	Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Intermediate Filament Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Axonemal A Tubule Inner Sheath Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Macromolecule Metabolic Process Ubiquitin Conjugating Enzyme Activity Nucleus Core-binding Factor Complex Apoptotic Process Involved In Embryonic Digit Morphogenesis Chromatin Regulation Of Base-excision Repair Broad Specificity Oxidative DNA Demethylase Activity
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