GEMIN7 and CEP126

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		GEMIN7	CEP126
Description		gem nuclear organelle associated protein 7	centrosomal protein 126
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies Sm-like Protein Family Complex	Cytoplasm Centrosome Cytoskeleton Midbody Cell Projection Ciliary Base
	Molecular Function	RNA Binding Protein Binding	Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	Mitotic Spindle Organization Cell Projection Organization Cytoplasmic Microtubule Organization Cilium Assembly Non-motile Cilium Assembly
Pathways		snRNP Assembly SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		20 interacting genes: ADD1 CEP126 EDRF1 FEZ1 GEMIN6 GOLM1 KAT5 RN7SL1 RNU1-1 RNU2-1 RPLP1 SHC1 SMN1 SNRPB SNRPD2 SNRPD3 SNRPE STRAP TAOK1 TUBA1A	87 interacting genes: AIMP2 AKTIP ARIH2 ATP6V1F ATRX BMI1 BRD1 C11orf58 CDKN2B CRCT1 CSTF2 DGCR6 DISC1 DLEU1 DNM1 DUSP12 DUSP23 EIF2S2 EIF6 EPN1 FAM118B FAM200C FEZ1 FGFR3 FXR1 GEMIN7 GET4 GIT1 GOLGB1 GPRASP2 GSTO1 HMOX2 HTT ING5 KAT5 KAT7 KIF15 KLHL20 LAMTOR5 LPL LRRC1 LUC7L2 MAD2L1BP MAPK9 MLH1 MRPS6 NAP1L5 NAT9 NPM3 NSF NUDT21 ODF2L OFD1 PBK PDCD5 PFDN1 PIK3R3 PMF1 POLD1 POLR2M PPP1CA PPP1CC PRKRA PTPRS RAB27A RAN RBM23 RETREG2 RGS2 RIF1 ROGDI RPA2 RUVBL1 SAT1 SNRPG SPDL1 STAU2 TFG TNFRSF14 TNFSF11 TOMM20 TTR TXNDC9 VIM YAE1 YWHAZ ZNF24
Entrez ID		79760	57562
HPRD ID		07600	17212
Ensembl ID		ENSG00000142252	ENSG00000110318
Uniprot IDs		Q9H840	Q9P2H0
PDB IDs		1Y96 7BBL
Enriched GO Terms of Interacting Partners?		SMN-Sm Protein Complex Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly Protein-RNA Complex Assembly U2 SnRNP 7-methylguanosine Cap Hypermethylation U4 SnRNP Methylosome Small Nuclear Ribonucleoprotein Complex RNA Splicing, Via Transesterification Reactions U1 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex PICln-Sm Protein Complex U2-type Spliceosomal Complex Cellular Component Assembly U2-type Catalytic Step 2 Spliceosome Protein-containing Complex Assembly U7 SnRNP MRNA Splicing, Via Spliceosome U4/U6 X U5 Tri-snRNP Complex RNA Splicing Protein-containing Complex Organization SMN Complex U2-type Precatalytic Spliceosome MRNA Processing U2 SnRNP Binding Precatalytic Spliceosome RNA Methylation Telomerase Holoenzyme Complex Catalytic Step 2 Spliceosome MRNA Metabolic Process Histone Pre-mRNA DCP Binding Macromolecule Methylation RNA Modification RNA Processing Spliceosomal Complex Nuclear Body Ribonucleoprotein Complex Gemini Of Cajal Bodies Methylation Protein Targeting To Vacuole Involved In Autophagy RNA Binding Nucleic Acid Metabolic Process Telomerase RNA Binding Negative Regulation Of Supramolecular Fiber Organization Cytoskeleton Organization Cytosol Protein Methylation	Nucleus Organelle Organization Cytosol Histone H3-K14 Acetyltransferase Complex Protein Binding Establishment Of Organelle Localization Phosphoprotein Phosphatase Activity Microtubule Cytoskeleton Organization Involved In Mitosis Protein-RNA Complex Assembly DNA Replication-dependent Chromatin Disassembly Organelle Localization Cytoplasm Chromatin Binding Presynapse Axon Positive Regulation Of Aggrephagy Histone Acetyltransferase Complex DNA Repair Chromosome, Telomeric Region Regulation Of Circadian Rhythm Chromosome Organization
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