GEMIN7 and RN7SL1

Number of citations of the paper that reports this interaction (PubMedID 23221635)
111

Data Source:
BioGRID (unspecified method)

		GEMIN7	RN7SL1
Description		gem nuclear organelle associated protein 7	RNA component of signal recognition particle 7SL1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies Sm-like Protein Family Complex	Signal Recognition Particle, Endoplasmic Reticulum Targeting
	Molecular Function	RNA Binding Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition
Pathways		snRNP Assembly SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		20 interacting genes: ADD1 CEP126 EDRF1 FEZ1 GEMIN6 GOLM1 KAT5 RN7SL1 RNU1-1 RNU2-1 RPLP1 SHC1 SMN1 SNRPB SNRPD2 SNRPD3 SNRPE STRAP TAOK1 TUBA1A	9 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GEMIN8 SMN1 STRAP
Entrez ID		79760	6029
HPRD ID		07600
Ensembl ID		ENSG00000142252	ENSG00000276168
Uniprot IDs		Q9H840
PDB IDs		1Y96 7BBL
Enriched GO Terms of Interacting Partners?		SMN-Sm Protein Complex Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly Protein-RNA Complex Assembly U2 SnRNP 7-methylguanosine Cap Hypermethylation U4 SnRNP Methylosome Small Nuclear Ribonucleoprotein Complex RNA Splicing, Via Transesterification Reactions U1 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex PICln-Sm Protein Complex U2-type Spliceosomal Complex Cellular Component Assembly U2-type Catalytic Step 2 Spliceosome Protein-containing Complex Assembly U7 SnRNP MRNA Splicing, Via Spliceosome U4/U6 X U5 Tri-snRNP Complex RNA Splicing Protein-containing Complex Organization SMN Complex U2-type Precatalytic Spliceosome MRNA Processing U2 SnRNP Binding Precatalytic Spliceosome RNA Methylation Telomerase Holoenzyme Complex Catalytic Step 2 Spliceosome MRNA Metabolic Process Histone Pre-mRNA DCP Binding Macromolecule Methylation RNA Modification RNA Processing Spliceosomal Complex Nuclear Body Ribonucleoprotein Complex Gemini Of Cajal Bodies Methylation Protein Targeting To Vacuole Involved In Autophagy RNA Binding Nucleic Acid Metabolic Process Telomerase RNA Binding Negative Regulation Of Supramolecular Fiber Organization Cytoskeleton Organization Cytosol Protein Methylation	SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies Spliceosomal SnRNP Assembly Protein-RNA Complex Assembly RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Protein-containing Complex Assembly Nuclear Body RNA Metabolic Process Protein-containing Complex Organization RNA Splicing, Via Transesterification Reactions Nucleic Acid Metabolic Process Cellular Component Assembly Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process Cytosol Nucleoplasm Nucleus Cytoplasm RNA Binding Cajal Body SMN-Gemin2 Complex Sm-like Protein Family Complex U2 SnRNP Binding U4atac SnRNA Binding U4 SnRNA Binding RNA Polymerase II Transcription Repressor Complex U1 SnRNA Binding SnRNA Binding Ribonucleoside Triphosphate Phosphatase Activity RNA 7-methylguanosine Cap Binding MRNA Binding Small Nuclear Ribonucleoprotein Complex Spliceosomal Tri-snRNP Complex Assembly DNA-templated Transcription Termination Maintenance Of Gastrointestinal Epithelium Alternative MRNA Splicing, Via Spliceosome
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