SMARCD3 and SMARCC1

Number of citations of the paper that reports this interaction (PMID 9891079)
41

Data Source:
HPRD (in vitro, in vivo)

		SMARCD3	SMARCC1
Gene Name		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm SWI/SNF Complex NpBAF Complex NBAF Complex	Nuclear Chromatin XY Body Nucleoplasm SWI/SNF Complex Protein Complex NpBAF Complex NBAF Complex
	Molecular Function	Transcription Coactivator Activity Receptor Binding Protein Binding Transcription Factor Binding Ligand-dependent Nuclear Receptor Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Nuclear Hormone Receptor Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Protein N-terminus Binding
	Biological Process	Positive Regulation Of Neuroblast Proliferation Secondary Heart Field Specification Cardiac Right Ventricle Formation Neural Retina Development Nucleosome Disassembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Muscle Cell Differentiation Regulation Of Protein Binding Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated	Chromatin Organization Nucleosome Disassembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Insulin Receptor Signaling Pathway Organ Morphogenesis ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Organelle biogenesis and maintenance Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Chromatin organization REV-ERBA represses gene expression RORA activates circadian gene expression Mitochondrial biogenesis RMTs methylate histone arginines Regulation of cholesterol biosynthesis by SREBP (SREBF) Chromatin modifying enzymes Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation YAP1- and WWTR1 (TAZ)-stimulated gene expression Activation of gene expression by SREBF (SREBP) Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Transcriptional activation of mitochondrial biogenesis BMAL1:CLOCK,NPAS2 activates circadian gene expression Orphan transporters	Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS		IgG glycosylation ( 23382691)
Protein-Protein Interactions		18 interactors: ARHGAP1 CCNE1 ESR1 ESRRA FANCA JUN MAPK14 NR1H4 NR5A1 NR5A2 PBX1 PPARG RARA RORA RXRA SMARCC1 SREBF1 STARD13	23 interactors: ADAMTSL4 ADD1 AKT1 CCNE1 CEBPB FANCA GATA1 ITCH KLF1 MSL1 MYC NEDD4 NONO NR3C1 OTX1 PLSCR1 PRMT5 RELB SIN3A SMARCA4 SMARCD3 SP1 SRC
Entrez ID		6604	6599
HPRD ID		03440	03435
Ensembl ID		ENSG00000082014	ENSG00000173473
Uniprot IDs		Q6STE5	Q58EY4 Q92922
PDB IDs			2YUS
Enriched GO Terms of Interacting Partners?		Steroid Hormone Mediated Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Hormone-mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Lipid Positive Regulation Of Gene Expression Cellular Response To Steroid Hormone Stimulus Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Cellular Response To Hormone Stimulus Response To Lipid Positive Regulation Of Metabolic Process Response To Steroid Hormone Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Cyclic Compound Transcription From RNA Polymerase II Promoter Response To Organic Cyclic Compound Response To Hormone Transcription, DNA-templated RNA Biosynthetic Process Cellular Response To Organic Substance Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Organ Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Organic Substance RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process System Development Signal Transduction Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Stimulus Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Signaling Cell Communication Multicellular Organismal Development Biosynthetic Process Steroid Metabolic Process Regulation Of Gene Expression Anatomical Structure Development	Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Organ Development Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Myeloid Cell Differentiation Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Cellular Metabolic Process Chromatin Organization Immune System Process In Utero Embryonic Development Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Expression Biosynthetic Process Chromatin Modification Erythrocyte Differentiation System Development Negative Regulation Of Signaling Regulation Of Metabolic Process Hemopoiesis Erythrocyte Homeostasis Response To Organic Substance Cellular Nitrogen Compound Metabolic Process Homeostasis Of Number Of Cells Negative Regulation Of Cellular Metabolic Process Regulation Of Binding Negative Regulation Of Gene Expression RNA Metabolic Process Immune System Development Myeloid Cell Homeostasis Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Chromosome Organization
Tagcloud ?		acetylase aldh1a3 belonging bipotent cbx6 ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 polycomb progenitors silico subpopulations trithorax	ae1 baf155 baf180 baf47 brg1 brm concurrent cytokeratin eosin epithelioid es hematoxylin hpb1 ini1 ini1expression mating nonfermentation pbrm1 pure reclassified rhabdoid snf2l2 snf5l4 sucrose switch vimentin
Tagcloud (Difference) ?		acetylase aldh1a3 belonging bipotent cbx6 ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 polycomb progenitors silico subpopulations trithorax	ae1 baf155 baf180 baf47 brg1 brm concurrent cytokeratin eosin epithelioid es hematoxylin hpb1 ini1 ini1expression mating nonfermentation pbrm1 pure reclassified rhabdoid snf2l2 snf5l4 sucrose switch vimentin
Tagcloud (Intersection) ?