SMARCC1 and KRTAP3-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SMARCC1	KRTAP3-1
Description		SWI/SNF related BAF chromatin remodeling complex subunit C1	keratin associated protein 3-1
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Chromatin Male Germ Cell Nucleus XY Body Nucleus Nucleoplasm Cytoplasm Nuclear Matrix SWI/SNF Complex RSC-type Complex Protein-containing Complex Brahma Complex NpBAF Complex NBAF Complex GBAF Complex	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding	Structural Molecule Activity Protein Binding
	Biological Process	Chromatin Organization Nucleosome Disassembly Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nervous System Development Positive Regulation Of Cell Population Proliferation Insulin Receptor Signaling Pathway Animal Organ Morphogenesis Regulation Of Mitotic Metaphase/anaphase Transition Prostate Gland Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of T Cell Differentiation Negative Regulation Of Cell Differentiation Positive Regulation Of Cell Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of G0 To G1 Transition Positive Regulation Of Stem Cell Population Maintenance Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Double-strand Break Repair Regulation Of Nucleotide-excision Repair
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of the polybromo-BAF (pBAF) complex Formation of the embryonic stem cell BAF (esBAF) complex Formation of the non-canonical BAF (ncBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)	Keratinization
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Household income (MTAG) ( 31844048) Renal underexcretion gout ( 32238385) Systolic blood pressure ( 31928498) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		53 interacting genes: ADAMTSL4 AKT1 CCNE1 CEBPB CFP CIDEB CYSRT1 EWSR1 FANCA FUS GATA1 GLRX3 GSTO2 ITCH KLF1 KRTAP13-3 KRTAP19-2 KRTAP21-2 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 LRP2BP MGAT5B MSL1 MYC NCOA1 NEDD4 NONO NR3C1 OTX1 PLSCR1 PPIP5K2 PTH1R RELB SIN3A SLC15A2 SMARCA4 SMARCD3 SP1 SPATA12 SREBF1 TAF15 TRIM42 UFSP1 USP7 VGLL3 ZNF581	83 interacting genes: ADAM12 AGXT ANAPC11 BMP7 CDKN1A CELA2B CERK CFP CIMIP1 CNNM3 CREB5 CTRC CYSRT1 DMRT3 DOCK2 FAM168A FAM222B FOXH1 FRS3 GATA2 GNE GPS2 GSTP1 HCK HEY2 HOXB9 HR HSF4 IL16 ITGB4 KRTAP10-8 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP6-1 KRTAP9-3 KRTAP9-8 LCE1B LCE2B LCE3A LCE3D LCE4A LCE5A LMO4 LRRC41 MAPKBP1 MRPL40 MYPOP NOTCH2NLA NTAQ1 OTX1 PATZ1 PCSK5 PHLDA1 PKIB PLSCR4 POLR1C PTPMT1 PVR RBPMS RECK REEP6 RNF44 SAMD7 SAXO4 SLC5A5 SMARCC1 SPAG8 SPMIP9 TEKT3 TLX3 TNS2 VASN VENTX VGLL3 WDR25 YPEL3 ZFHX2 ZNF414 ZNF446
Entrez ID		6599	83896
HPRD ID		03435	13937
Ensembl ID		ENSG00000173473	ENSG00000212901
Uniprot IDs		Q58EY4 Q92922	Q9BYR8
PDB IDs		2YUS 5GJK 6KZ7 6YXO 6YXP
Enriched GO Terms of Interacting Partners?		Intermediate Filament Transcription Coregulator Binding Chromatin Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein-containing Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Cellular Response To Hormone Stimulus Rhythmic Process Chromatin Binding Positive Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of MiRNA Transcription Protein Binding DNA-binding Transcription Factor Activity Protein-DNA Complex Disassembly Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Repressor Complex Positive Regulation Of MiRNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Response To Ketone Identical Protein Binding Intracellular Receptor Signaling Pathway Negative Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MiRNA Transcription Nuclear Receptor-mediated Corticosteroid Signaling Pathway DNA Binding Regulation Of MiRNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Keratin Filament Cellular Response To Peptide Hormone Stimulus Regulation Of Primary Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Alpha-beta T Cell Activation Transcription By RNA Polymerase II Positive Regulation Of Innate Immune Response Nucleoplasm Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Innate Immune Response Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Defense Response Regulation Of Signal Transduction By P53 Class Mediator Protein K29-linked Ubiquitination Progesterone Receptor Signaling Pathway Response To Hormone Transcription Coregulator Activity	Intermediate Filament Protein Binding Keratinization Keratin Filament Epidermis Development Axonemal A Tubule Inner Sheath Tissue Development Ventral Spinal Cord Interneuron Differentiation Heart Trabecula Morphogenesis Cellular Response To Cell-matrix Adhesion
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