SMARCC1 and CEBPB

Number of citations of the paper that reports this interaction (PMID 10619021)
88

Data Source:
HPRD (in vivo)

		SMARCC1	CEBPB
Gene Name		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	CCAAT/enhancer binding protein (C/EBP), beta
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Gene Ontology Annotations	Cellular Component	Nuclear Chromatin XY Body Nucleoplasm SWI/SNF Complex Protein Complex NpBAF Complex NBAF Complex	Condensed Chromosome, Centromeric Region Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Protein N-terminus Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Glucocorticoid Receptor Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Chromatin Organization Nucleosome Disassembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Insulin Receptor Signaling Pathway Organ Morphogenesis ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Embryonic Placenta Development Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Acute-phase Response Inflammatory Response Immune Response Neuron Differentiation Response To Lipopolysaccharide Mammary Gland Epithelial Cell Proliferation Response To Endoplasmic Reticulum Stress Negative Regulation Of Neuron Apoptotic Process Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Brown Fat Cell Differentiation Mammary Gland Epithelial Cell Differentiation Regulation Of Transcription Involved In Cell Fate Commitment Cellular Response To Amino Acid Stimulus
Pathways		Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines	Transcriptional regulation of white adipocyte differentiation Cellular Senescence Senescence-Associated Secretory Phenotype (SASP)
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		23 interactors: ADAMTSL4 ADD1 AKT1 CCNE1 CEBPB FANCA GATA1 ITCH KLF1 MSL1 MYC NEDD4 NONO NR3C1 OTX1 PLSCR1 PRMT5 RELB SIN3A SMARCA4 SMARCD3 SP1 SRC	54 interactors: AR ATF2 ATF4 CAMK2A CCL3 CEBPA CEBPD CEBPG CREB1 CREBBP DDIT3 EGFR EGR1 ELK1 EP300 ESR1 FOXO1 HMGA1 HMGB1 HNRNPK HOMER3 HSF1 KAT2A KAT2B MAPK1 MAPK3 MED23 MYB MYC NCOR2 NFKB1 NOLC1 NR3C1 PTGES2 RARB RB1 RELA RPS6KA1 RPS6KA5 RUNX1 RUNX2 SMAD3 SMAD4 SMARCA4 SMARCB1 SMARCC1 SP1 SPI1 SPIB SRF STAT5A STAT6 TAF9 TRIM28
Entrez ID		6599	1051
HPRD ID		03435	01801
Ensembl ID		ENSG00000173473	ENSG00000172216
Uniprot IDs		Q58EY4 Q92922	P17676
PDB IDs		2YUS	1GTW 1GU4 1GU5 1H88 1H89 1H8A 1HJB 1IO4 2E42 2E43
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Organ Development Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Myeloid Cell Differentiation Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Cellular Metabolic Process Chromatin Organization Immune System Process In Utero Embryonic Development Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Expression Biosynthetic Process Chromatin Modification Erythrocyte Differentiation System Development Negative Regulation Of Signaling Regulation Of Metabolic Process Hemopoiesis Erythrocyte Homeostasis Response To Organic Substance Cellular Nitrogen Compound Metabolic Process Homeostasis Of Number Of Cells Negative Regulation Of Cellular Metabolic Process Regulation Of Binding Negative Regulation Of Gene Expression RNA Metabolic Process Immune System Development Myeloid Cell Homeostasis Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Chromosome Organization	Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Organic Substance Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Response To Organic Substance Negative Regulation Of RNA Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Gene Expression DNA-templated Transcription, Initiation Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Immune System Process Cellular Metabolic Process System Development Developmental Process Gland Development Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Multicellular Organismal Development Cellular Response To Stimulus Negative Regulation Of Cellular Metabolic Process Anatomical Structure Development Organ Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Growth Factor Stimulus
Tagcloud ?		ae1 baf155 baf180 baf47 brg1 brm concurrent cytokeratin eosin epithelioid es hematoxylin hpb1 ini1 ini1expression mating nonfermentation pbrm1 pure reclassified rhabdoid snf2l2 snf5l4 sucrose switch vimentin	activates anticancer atf4 attenuated autophagy chip ddit4 depletion effectively elusive exo genomic greatly largely mitochondria mtorc1 nude pad pan perturbation potentials remain resolution responsive sesn2 triple unveiled xenograft yw3
Tagcloud (Difference) ?		ae1 baf155 baf180 baf47 brg1 brm concurrent cytokeratin eosin epithelioid es hematoxylin hpb1 ini1 ini1expression mating nonfermentation pbrm1 pure reclassified rhabdoid snf2l2 snf5l4 sucrose switch vimentin	activates anticancer atf4 attenuated autophagy chip ddit4 depletion effectively elusive exo genomic greatly largely mitochondria mtorc1 nude pad pan perturbation potentials remain resolution responsive sesn2 triple unveiled xenograft yw3
Tagcloud (Intersection) ?