SMARCC1

Name	SWI/SNF related BAF chromatin remodeling complex subunit C1
Structure
Novel Interactors	1 novel interactors: STT3B
Interactors	53 interactors: ADAMTSL4 AKT1 CCNE1 CEBPB CFP CIDEB CYSRT1 EWSR1 FANCA FUS GATA1 GLRX3 GSTO2 ITCH KLF1 KRTAP13-3 KRTAP19-2 KRTAP21-2 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 LRP2BP MGAT5B MSL1 MYC NCOA1 NEDD4 NONO NR3C1 OTX1 PLSCR1 PPIP5K2 PTH1R RELB SIN3A SLC15A2 SMARCA4 SMARCD3 SP1 SPATA12 SREBF1 TAF15 TRIM42 UFSP1 USP7 VGLL3 ZNF581
GO Annotations	Cellular Component	Kinetochore Chromatin Male Germ Cell Nucleus XY Body Nucleus Nucleoplasm Cytoplasm Nuclear Matrix SWI/SNF Complex RSC-type Complex Protein-containing Complex Brahma Complex NpBAF Complex NBAF Complex GBAF Complex
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding
	Biological Process	Chromatin Organization Nucleosome Disassembly Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nervous System Development Positive Regulation Of Cell Population Proliferation Insulin Receptor Signaling Pathway Animal Organ Morphogenesis Regulation Of Mitotic Metaphase/anaphase Transition Prostate Gland Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of T Cell Differentiation Negative Regulation Of Cell Differentiation Positive Regulation Of Cell Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of G0 To G1 Transition Positive Regulation Of Stem Cell Population Maintenance Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Double-strand Break Repair Regulation Of Nucleotide-excision Repair
Pathways	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of the polybromo-BAF (pBAF) complex Formation of the embryonic stem cell BAF (esBAF) complex Formation of the non-canonical BAF (ncBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
GWAS	Age at first birth ( 34211149 ) Household income (MTAG) ( 31844048 ) Renal underexcretion gout ( 32238385 ) Systolic blood pressure ( 31928498 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Entrez ID	6599
HPRD ID	03435
Ensembl ID	ENSG00000173473
Uniprot IDs	Q58EY4 Q92922
PDB IDs	2YUS 5GJK 6KZ7 6YXO 6YXP
GO Terms Enriched among Interactors ?	Intermediate Filament Transcription Coregulator Binding Chromatin Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein-containing Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Cellular Response To Hormone Stimulus Rhythmic Process Chromatin Binding Positive Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of MiRNA Transcription Protein Binding DNA-binding Transcription Factor Activity Protein-DNA Complex Disassembly Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Repressor Complex Positive Regulation Of MiRNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Response To Ketone Identical Protein Binding Intracellular Receptor Signaling Pathway Negative Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MiRNA Transcription Nuclear Receptor-mediated Corticosteroid Signaling Pathway DNA Binding Regulation Of MiRNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Keratin Filament Cellular Response To Peptide Hormone Stimulus Regulation Of Primary Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Alpha-beta T Cell Activation Transcription By RNA Polymerase II Positive Regulation Of Innate Immune Response Nucleoplasm Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Innate Immune Response Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Defense Response Regulation Of Signal Transduction By P53 Class Mediator Protein K29-linked Ubiquitination Progesterone Receptor Signaling Pathway Response To Hormone Transcription Coregulator Activity