GRAMD2B and GIMAP5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		GRAMD2B	GIMAP5
Description		GRAM domain containing 2B	GTPase, IMAP family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoplasmic Microtubule	Lysosome Lysosomal Membrane Endosome Endosome Membrane Membrane Multivesicular Body Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Tuberculosis ( 30713548) Vaginal microbiome composition (L. crispatus) ( 32723796)
Interacting Genes		11 interacting genes: ABO CD207 CDC37 FRMD8 GIMAP5 MORF4L2 NAPRT PAEP SEC22A TMEM43 VAMP5	68 interacting genes: ADGRG3 APP AQP3 AQP6 ARL13B BTNL9 CD33 CD53 CLDN7 CREB3L1 CYB561 CYBRD1 DKK4 EBP EDA EDA2R ELOVL4 EMP1 ERGIC3 EVI2B FAM174A FAM209A FAM210B FATE1 FCER1G GJA8 GJB3 GORAB GPR42 GRAMD2B IFNGR2 JAGN1 KASH5 KIR3DL3 LAYN LDLRAD1 LSMEM2 M6PR MGST2 MGST3 MILR1 MS4A14 PDZK1IP1 PTGES RETREG3 RNASEK RNF19B SCN3B SHISAL1 SLC10A1 SLC10A6 SLC35H1 SMIM3 SPACA1 STOM STX1A STX2 STX4 SYT1 TM4SF18 TM4SF19 TMEM31 TMX1 TMX2 TNFRSF19 TSPAN18 ZER1 ZFYVE27
Entrez ID		65983	55340
HPRD ID		11402	16280
Ensembl ID		ENSG00000155324	ENSG00000196329
Uniprot IDs		Q96HH9	A0A090N8P9 Q96F15
PDB IDs			6Z3E
Enriched GO Terms of Interacting Partners?		Glycoprotein-fucosylgalactoside Alpha-N-acetylgalactosaminyltransferase Activity Fucosylgalactoside 3-alpha-galactosyltransferase Activity Negative Regulation Of Sperm Capacitation Nicotinate Phosphoribosyltransferase Activity	Membrane Protein Binding Exocytosis Plasma Membrane Endoplasmic Reticulum Membrane Secretion By Cell Identical Protein Binding Ascorbate Homeostasis Secretion Positive Regulation Of Regulated Secretory Pathway Regulated Exocytosis Glutathione Peroxidase Activity Transmembrane Monodehydroascorbate Reductase Activity Endomembrane System Vesicle Docking Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site SNARE Binding Tertiary Granule Membrane Leukotriene-C4 Synthase Activity Bile Acid:sodium Symporter Activity Vesicle-mediated Transport Glutathione Transferase Activity Cornified Envelope Assembly Endoplasmic Reticulum Organelle Localization By Membrane Tethering Calcium-ion Regulated Exocytosis Specific Granule Membrane Positive Regulation Of Exocytosis Renal Water Transport Chromaffin Granule Membrane Membrane Docking SNAP Receptor Activity Disulfide Oxidoreductase Activity Vesicle Fusion Glutathione Binding Icosanoid Biosynthetic Process Tumor Necrosis Factor Receptor Activity Nuclear Envelope Lumen SNARE Complex Organelle Membrane Fusion Positive Regulation Of Catecholamine Secretion SNARE Complex Assembly
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