KRTAP4-11 and LCE5A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP4-11	LCE5A
Description		keratin associated protein 4-11	late cornified envelope 5A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Hair Cycle	Epidermis Development Keratinization
Pathways		Keratinization	Formation of the cornified envelope
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma and eczema ( 34155719) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic march ( 26542096) Hair morphology ( 19896111) Heel bone mineral density x serum urate levels interaction ( 34046847) Inflammatory skin disease ( 25574825)
Interacting Genes		90 interacting genes: ADAMTSL4 CATSPER1 CRCT1 CREB5 CYSRT1 DHRS1 EHHADH ENKD1 EPDR1 FAM221A FAM76B FBXO34 GATA1 GLRX3 GNE GRAP2 HOXA1 KLHL38 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP15-1 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-3 KRTAP4-2 KRTAP4-4 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NECTIN3 NOTCH2NLA NR4A3 NUFIP2 OTX1 P4HB PLSCR1 POTEB3 POU4F2 PRPF31 RGS17 SHFL SLC23A1 SMCP SPRY2 TGFB1 TSPAN4 VASN VGLL3 ZNF417 ZNF552 ZNF837	88 interacting genes: ADAM12 ADAMTSL4 ALPP CATSPER1 CHIC2 CHRD CREB5 CYP21A2 CYSRT1 FBLN1 GRN HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP2-3 KRTAP2-4 KRTAP21-2 KRTAP3-1 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-8 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE4A MACO1 NBPF19 NECTIN2 NOTCH2NLA NTAQ1 NUFIP2 NUTF2 PLA2G10 PLAC8 PLSCR2 PLSCR3 PLSCR4 POU4F2 RGS17 RGS20 RNF4 SLC39A7 SMCP SPRED2 SPRY1 TGFB1 TRIM42 UBE2I VASN VWC2 VWC2L ZNF655
Entrez ID		653240	254910
HPRD ID			17265
Ensembl ID		ENSG00000212721	ENSG00000186207
Uniprot IDs		Q9BYQ6	Q5TCM9
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Identical Protein Binding Protein Binding	Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Identical Protein Binding Protein Binding Phospholipid Scramblase Activity Negative Regulation Of Lens Fiber Cell Differentiation Plasma Membrane Phospholipid Scrambling Cytosol Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
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