LCE5A and MACO1

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		LCE5A	MACO1
Description		late cornified envelope 5A	macoilin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Endoplasmic Reticulum Membrane Axon Rough Endoplasmic Reticulum Membrane Nuclear Membrane Cell Projection Neuron Projection Neuron Projection Terminus Synapse
	Molecular Function	Protein Binding Identical Protein Binding	Molecular_function Protein Binding Microtubule Binding
	Biological Process	Epidermis Development Keratinization	Chemotaxis Brain Development Neuronal Signal Transduction
Pathways		Formation of the cornified envelope	RHOA GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma and eczema ( 34155719) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic march ( 26542096) Hair morphology ( 19896111) Heel bone mineral density x serum urate levels interaction ( 34046847) Inflammatory skin disease ( 25574825)	LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
Interacting Genes		88 interacting genes: ADAM12 ADAMTSL4 ALPP CATSPER1 CHIC2 CHRD CREB5 CYP21A2 CYSRT1 FBLN1 GRN HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP2-3 KRTAP2-4 KRTAP21-2 KRTAP3-1 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-8 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE4A MACO1 NBPF19 NECTIN2 NOTCH2NLA NTAQ1 NUFIP2 NUTF2 PLA2G10 PLAC8 PLSCR2 PLSCR3 PLSCR4 POU4F2 RGS17 RGS20 RNF4 SLC39A7 SMCP SPRED2 SPRY1 TGFB1 TRIM42 UBE2I VASN VWC2 VWC2L ZNF655	26 interacting genes: CRCT1 HOXA1 KRTAP5-2 KRTAP5-7 LCE1A LCE1C LCE1D LCE1E LCE1F LCE2C LCE3A LCE3D LCE3E LCE5A LINGO1 MEI4 MEOX2 NBPF19 NOTCH2NLA NR4A3 POTEB3 SMAD9 SMCP SRPK2 TMEM190 ZNF655
Entrez ID		254910	55219
HPRD ID		17265	13340
Ensembl ID		ENSG00000186207	ENSG00000204178
Uniprot IDs		Q5TCM9	Q8N5G2
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Identical Protein Binding Protein Binding Phospholipid Scramblase Activity Negative Regulation Of Lens Fiber Cell Differentiation Plasma Membrane Phospholipid Scrambling Cytosol Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway	Keratinization Epidermis Development Tissue Development Developmental Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?