KRTAP4-11 and EPDR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP4-11	EPDR1
Description		keratin associated protein 4-11	ependymin related 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Extracellular Region Lysosome Lysosomal Lumen
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Phospholipid Binding Lipid Binding Identical Protein Binding Ganglioside GM1 Binding
	Biological Process	Hair Cycle	Cell-matrix Adhesion Myofibroblast Contraction
Pathways		Keratinization
Drugs
Diseases
GWAS			Dupuytren's disease ( 21732829 28886342) Glaucoma (primary angle closure) ( 27064256) Heel bone mineral density ( 28869591 30598549) Height ( 31562340) Lateral ventricle volume ( 31530798) Lumbar spine bone mineral density ( 29499414) Rosacea symptom severity ( 29771307)
Interacting Genes		90 interacting genes: ADAMTSL4 CATSPER1 CRCT1 CREB5 CYSRT1 DHRS1 EHHADH ENKD1 EPDR1 FAM221A FAM76B FBXO34 GATA1 GLRX3 GNE GRAP2 HOXA1 KLHL38 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP15-1 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-3 KRTAP4-2 KRTAP4-4 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NECTIN3 NOTCH2NLA NR4A3 NUFIP2 OTX1 P4HB PLSCR1 POTEB3 POU4F2 PRPF31 RGS17 SHFL SLC23A1 SMCP SPRY2 TGFB1 TSPAN4 VASN VGLL3 ZNF417 ZNF552 ZNF837	13 interacting genes: ADAMTSL4 EHMT2 HOXA1 IGFBP6 KRT31 KRT34 KRTAP10-8 KRTAP13-2 KRTAP4-11 PM20D2 TNS2 TRIP6 UBQLN4
Entrez ID		653240	54749
HPRD ID			16865
Ensembl ID		ENSG00000212721	ENSG00000086289
Uniprot IDs		Q9BYQ6	Q96J80 Q9UM22
PDB IDs			6E7O 6E8N 6JLD
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Identical Protein Binding Protein Binding	Keratin Filament Intermediate Filament Identical Protein Binding Structural Molecule Activity Negative Regulation Of Macroautophagy Semicircular Canal Formation Insulin-like Growth Factor Binary Complex Histone H3K56 Methyltransferase Activity Pigment Cell Development Para-aminobenzoyl-glutamate Hydrolase Activity Structural Constituent Of Skin Epidermis Abducens Nerve Formation Optokinetic Behavior Intermediate Filament Organization Nuclear Proteasome Complex Folic Acid Catabolic Process Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Phenotypic Switching Negative Regulation Of Autophagosome Maturation Kinase Binding Negative Regulation Of Autophagy
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