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SKIL and KRT81
Number of citations of the paper that reports this interaction (PubMedID
15231748
)
54
Data Source:
HPRD
(two hybrid)
SKIL
KRT81
Description
SKI like proto-oncogene
keratin 81
Image
No pdb structure
GO Annotations
Cellular Component
Acrosomal Vesicle
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
PML Body
Protein-containing Complex
Extracellular Space
Cytosol
Intermediate Filament
Keratin Filament
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Chromatin Binding
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Protein-containing Complex Binding
SMAD Binding
Protein Binding
Structural Constituent Of Skin Epidermis
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Blastocyst Formation
Lymphocyte Homeostasis
Transforming Growth Factor Beta Receptor Signaling Pathway
Spermatogenesis
Skeletal Muscle Tissue Development
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Cell Differentiation
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of BMP Signaling Pathway
Response To Cytokine
Negative Regulation Of Cell Differentiation
Response To Antibiotic
Regulation Of Neurogenesis
Positive Regulation Of Axonogenesis
Regulation Of Cell Cycle
Muscle Structure Development
Lens Fiber Cell Differentiation
Response To Growth Factor
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Keratinization
Intermediate Filament Organization
Pathways
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Keratinization
Formation of the cornified envelope
Drugs
Diseases
Monilethrix
GWAS
Aspartate aminotransferase levels (
33547301
)
Estimated glomerular filtration rate (
31152163
)
Glomerular filtration rate (creatinine) (
26831199
)
Glomerular filtration rate in non diabetics (creatinine) (
26831199
)
Prostate cancer (
21743467
)
Diisocyanate-induced asthma (
25918132
)
Interacting Genes
97 interacting genes:
ASCC3
CAMSAP1
CBX4
CDC16
CDC27
CHD3
CHPF
COL4A2
CPNE1
CPNE2
CPNE4
CXXC5
DEUP1
DHX30
DRC4
DRG1
DSCAM
EEF1G
EIF4G2
ESR1
FAF1
FBLN1
FN1
FZR1
GLUL
GOLGB1
HEY1
HEYL
HIPK1
HIPK3
HNRNPLL
IL36RN
KRT81
LRP1
MACF1
MORC4
MVP
MYG1
NCOR1
NCOR2
NEFL
NID1
NID2
NXF3
OIP5
PAPPA
PIAS1
PIAS3
PIAS4
PLCD3
PPL
PSG3
PSMC2
PTPRF
PYCR2
RNF4
RPS27
SASH1
SETDB1
SKI
SMAD1
SMAD2
SMAD3
SMAD4
SMUG1
SMURF2
SNRNP70
SNX17
SPARCL1
SRP72
STK16
SVEP1
TDG
TDP2
TFPI2
THAP5
THSD7A
TLE5
TPM2
TRAK1
TRIM62
TRIM69
TSKU
TTF2
UBE2I
UIMC1
USP25
VPS28
XPA
XRCC6
ZBTB3
ZBTB6
ZMYM2
ZMYM5
ZNF106
ZNF200
ZZEF1
30 interacting genes:
CYSRT1
DMRTB1
HOXA1
KRT13
KRT14
KRT15
KRT16
KRT18
KRT19
KRT24
KRT25
KRT26
KRT27
KRT28
KRT31
KRT33B
KRT34
KRT35
KRT36
KRT37
KRT38
KRT39
KRT40
KXD1
LCA5L
MEOX2
OIP5
OTX1
PCBP3
SKIL
Entrez ID
6498
3887
HPRD ID
01319
03691
Ensembl ID
ENSG00000136603
ENSG00000205426
Uniprot IDs
P12757
Q14533
PDB IDs
3EQ5
5C4V
Enriched GO Terms of Interacting Partners
?
PML Body
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
SMAD Protein Complex
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Nucleus
Heteromeric SMAD Protein Complex
SUMO Transferase Activity
Nucleoplasm
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Macromolecule Metabolic Process
SUMO Ligase Activity
I-SMAD Binding
Collagen Binding
Regulation Of Macromolecule Metabolic Process
Response To Transforming Growth Factor Beta
Regulation Of MiRNA Transcription
Protein Metabolic Process
Metal Ion Binding
Protein Modification By Small Protein Conjugation
Nuclear Body
Cell Surface Receptor Signaling Pathway
Regulation Of Primary Metabolic Process
SMAD Protein Signal Transduction
Protein Sumoylation
Regulation Of MiRNA Metabolic Process
Negative Regulation Of MiRNA Transcription
Zinc Ion Binding
Regulation Of Metabolic Process
Cytoplasm
Transforming Growth Factor Beta Receptor Signaling Pathway
Cellular Response To Transforming Growth Factor Beta Stimulus
SUMO Binding
Homomeric SMAD Protein Complex
Negative Regulation Of Transforming Growth Factor Beta Production
Co-SMAD Binding
Regulation Of Gene Expression
Regulation Of Developmental Process
Extracellular Matrix Structural Constituent
Primary MiRNA Processing
Positive Regulation Of Protein Sumoylation
Regulation Of Protein Catabolic Process
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Cytosol
Structural Constituent Of Skin Epidermis
Intermediate Filament Cytoskeleton Organization
Keratin Filament
Intermediate Filament-based Process
Intermediate Filament Organization
Intermediate Filament
Structural Molecule Activity
Epithelial Cell Differentiation
Morphogenesis Of An Epithelium
Tissue Morphogenesis
Supramolecular Fiber Organization
Cytoskeleton Organization
Anatomical Structure Morphogenesis
Cytoskeleton
Extracellular Exosome
Cell Differentiation
Developmental Process
Organelle Organization
Cellular Developmental Process
Hair Cycle
Epidermis Development
Structural Constituent Of Cytoskeleton
Cytosol
Hair Follicle Morphogenesis
Tissue Development
Cornified Envelope
Hair Cycle Process
Cell Periphery
Protein Binding
Semicircular Canal Formation
Diencephalon Morphogenesis
C-rich Single-stranded DNA Binding
Establishment Of Skin Barrier
Skin Epidermis Development
Abducens Nerve Formation
Optokinetic Behavior
Intermediate Filament Cytoskeleton
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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