MRPL38 and RALY

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MRPL38	RALY
Description		mitochondrial ribosomal protein L38	RALY heterogeneous nuclear ribonucleoprotein
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Cytosol Ribosome Ribonucleoprotein Complex	Nucleus Spliceosomal Complex Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	Protein Binding	Nucleic Acid Binding Transcription Coregulator Activity RNA Binding Protein Binding
	Biological Process	Mitochondrial Translation	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Cholesterol Homeostasis
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		White matter hyperintensities ( 30002152)	Adult body size ( 32376654) Basal cell carcinoma ( 33549134 27539887 31174203) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 22976474) Cancer ( 27197191) Cancer (pleiotropy) ( 27197191) Cutaneous malignant melanoma ( 32341527) Cutaneous squamous cell carcinoma ( 32041948) Estimated glomerular filtration rate ( 31451708) Facial pigmentation ( 25705849) Hair color ( 29662168) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Idiopathic dilated cardiomyopathy ( 29495422) Keratinocyte cancer (MTAG) ( 31174203) Low tan response ( 29739929) Melanoma ( 28212542) Nevus count or cutaneous melanoma ( 32341527) Non-melanoma skin cancer ( 29739929) Red cell distribution width ( 32888494) Red vs. brown/black hair color ( 30531825) Refractive error ( 32231278) Skin colour saturation ( 25963972) Skin sensitivity to sun ( 25963972) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Squamous cell carcinoma ( 26829030) Type 2 diabetes ( 30297969) Vitiligo ( 27723757) Weight ( 28552196) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		21 interacting genes: ARHGAP9 BAG3 BEX2 BTG3 CCDC120 CENATAC CSNK2A1 DOCK8 ENKD1 ERCC6 ERG28 GOLGA6A HSPB3 LONRF1 MKRN3 MYOZ3 PPP1R18 PRIM1 RALY TSEN54 UBC	30 interacting genes: BCCIP BYSL CELF1 EXOC7 GTPBP3 HNRNPD HNRNPH1 HNRNPK HSF2BP KHDRBS1 LNX1 MDM2 MRPL38 MTUS2 PCBP1 PIK3CD PLOD3 PRKN QKI RBPMS2 RPL9 SDCBP SPG7 THAP1 TIGD3 USP7 WDR62 ZBTB24 ZNF408 ZNF76
Entrez ID		64978	22913
HPRD ID		14758	11480
Ensembl ID		ENSG00000204316	ENSG00000125970
Uniprot IDs		Q96DV4	Q53GL6 Q9UKM9
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI6 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU1 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3	1WF1
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Aggrephagy Double-strand Break Repair Via Classical Nonhomologous End Joining	Nucleic Acid Binding MRNA Binding Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process Ribonucleoprotein Complex Regulation Of MRNA Processing Response To Ether Nucleic Acid Metabolic Process RNA Metabolic Process Nucleus Regulation Of MRNA Metabolic Process Cytoplasmic Stress Granule RNA Binding Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Retrograde Transport, Endosome To Golgi RNA Processing Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Telomere Capping Positive Regulation Of Catabolic Process Regulation Of Exosomal Secretion Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Poly(U) RNA Binding Protein Binding Negative Regulation Of MRNA Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Postsynaptic Density Regulation Of Macromolecule Biosynthetic Process MRNA Processing SH3 Domain Binding Positive Regulation Of MRNA Catabolic Process Cytosol Cytoplasm Regulation Of Primary Metabolic Process Amyloid Fibril Formation Regulation Of Intracellular Transport Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Hepatocyte Dedifferentiation Cellular Response To Putrescine Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Formaldehyde Cellular Response To Vitamin B1
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