RALY

Description		RALY heterogeneous nuclear ribonucleoprotein
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GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	Nucleic Acid Binding Transcription Coregulator Activity RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Cholesterol Homeostasis
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Basal cell carcinoma ( 33549134 27539887 31174203) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 22976474) Cancer ( 27197191) Cancer (pleiotropy) ( 27197191) Cutaneous malignant melanoma ( 32341527) Cutaneous squamous cell carcinoma ( 32041948) Estimated glomerular filtration rate ( 31451708) Facial pigmentation ( 25705849) Hair color ( 29662168) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Idiopathic dilated cardiomyopathy ( 29495422) Keratinocyte cancer (MTAG) ( 31174203) Low tan response ( 29739929) Melanoma ( 28212542) Nevus count or cutaneous melanoma ( 32341527) Non-melanoma skin cancer ( 29739929) Red cell distribution width ( 32888494) Red vs. brown/black hair color ( 30531825) Refractive error ( 32231278) Skin colour saturation ( 25963972) Skin sensitivity to sun ( 25963972) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Squamous cell carcinoma ( 26829030) Type 2 diabetes ( 30297969) Vitiligo ( 27723757) Weight ( 28552196) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		30 interacting genes: BCCIP BYSL CELF1 EXOC7 GTPBP3 HNRNPD HNRNPH1 HNRNPK HSF2BP KHDRBS1 LNX1 MDM2 MRPL38 MTUS2 PCBP1 PIK3CD PLOD3 PRKN QKI RBPMS2 RPL9 SDCBP SPG7 THAP1 TIGD3 USP7 WDR62 ZBTB24 ZNF408 ZNF76
Entrez ID		22913
HPRD ID		11480
Ensembl ID		ENSG00000125970
Uniprot IDs		Q53GL6 Q9UKM9
PDB IDs		1WF1
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding MRNA Binding Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process Ribonucleoprotein Complex Regulation Of MRNA Processing Response To Ether Nucleic Acid Metabolic Process RNA Metabolic Process Nucleus Regulation Of MRNA Metabolic Process Cytoplasmic Stress Granule RNA Binding Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Retrograde Transport, Endosome To Golgi RNA Processing Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Telomere Capping Positive Regulation Of Catabolic Process Regulation Of Exosomal Secretion Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Poly(U) RNA Binding Protein Binding Negative Regulation Of MRNA Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Postsynaptic Density Regulation Of Macromolecule Biosynthetic Process MRNA Processing SH3 Domain Binding Positive Regulation Of MRNA Catabolic Process Cytosol Cytoplasm Regulation Of Primary Metabolic Process Amyloid Fibril Formation Regulation Of Intracellular Transport Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Hepatocyte Dedifferentiation Cellular Response To Putrescine Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Formaldehyde Cellular Response To Vitamin B1
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