MRPL38 and ARHGAP9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MRPL38	ARHGAP9
Description		mitochondrial ribosomal protein L38	Rho GTPase activating protein 9
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Cytosol Ribosome Ribonucleoprotein Complex	Extracellular Region Cytoplasm Cytosol Plasma Membrane Secretory Granule Lumen
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Lipid Binding
	Biological Process	Mitochondrial Translation	Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control	Neutrophil degranulation RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		White matter hyperintensities ( 30002152)	Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494)
Interacting Genes		21 interacting genes: ARHGAP9 BAG3 BEX2 BTG3 CCDC120 CENATAC CSNK2A1 DOCK8 ENKD1 ERCC6 ERG28 GOLGA6A HSPB3 LONRF1 MKRN3 MYOZ3 PPP1R18 PRIM1 RALY TSEN54 UBC	17 interacting genes: ABI3 AKT1 APP CYSRT1 FASLG FHL2 GOLGA6A GOLGA6L9 HOMEZ MRPL38 NME7 RAC1 RBPMS RUNX1T1 SMAD9 SNRPC TSC22D4
Entrez ID		64978	64333
HPRD ID		14758	06449
Ensembl ID		ENSG00000204316	ENSG00000123329
Uniprot IDs		Q96DV4	B3KQ74 Q9BRR9
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI6 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU1 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3	2P0D 2P0F 2P0H
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Aggrephagy Double-strand Break Repair Via Classical Nonhomologous End Joining	Regulation Of Postsynapse Organization Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Postsynapse Sphingosine-1-phosphate Receptor Signaling Pathway Sphingolipid Mediated Signaling Pathway Regulation Of Synapse Organization Osteoblast Differentiation Response To Growth Factor SMAD Protein Signal Transduction Regulation Of Extrinsic Apoptotic Signaling Pathway Lymphocyte Apoptotic Process T Cell Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Toll-like Receptor Signaling Pathway Lamellipodium Regulation Of Fibroblast Migration Response To Nerve Growth Factor Regulation Of Protein Localization To Membrane Regulation Of TRNA Methylation Positive Regulation Of Nitric Oxide Metabolic Process Cellular Response To Nerve Growth Factor Stimulus Amyloid-beta Complex Dendritic Shaft Regulation Of Synapse Assembly Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Dendrite Development Regulation Of Ruffle Assembly Regulation Of Lamellipodium Assembly Leukocyte Apoptotic Process Homeostatic Process Chemical Homeostasis Intracellular Signaling Cassette Negative Regulation Of Protein Localization Regulation Of Lamellipodium Organization Regulation Of Neuron Apoptotic Process Regulation Of Leukocyte Migration Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cell Projection Assembly Negative Regulation Of RNA Metabolic Process Response To Peptide Response To Cytokine Negative Regulation Of Protein Localization To Lysosome Acetylcholine Receptor Activator Activity Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
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