MRPS11 and PRPF6

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		MRPS11	PRPF6
Description		mitochondrial ribosomal protein S11	pre-mRNA processing factor 6
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Ribosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Centrosome Cytosol Membrane Nuclear Speck Ciliary Basal Body U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	RNA Binding Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Ribonucleoprotein Complex Binding
	Biological Process	Translation Mitochondrial Translation	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing RNA Localization RNA Splicing Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Familial hepatitis B virus-related hepatocellular carcinoma ( 28662289)	Body mass index ( 28552196) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: KRT31 NAA10 PRPF6 SRPK1	67 interacting genes: AR ARAF BAG4 BICD2 C1orf35 CD2BP2 CEBPA CEP55 CLK2 CPSF7 CTBP1 CTTN DDX17 DMRTB1 EFTUD2 EHMT2 ESR1 EXOSC7 EXOSC8 FHIT FXR2 HNRNPLL HOOK1 IDH3A KIF24 KRT31 LARP4 LMNA MRPL1 MRPL44 MRPS11 NIN NME1 NR3C1 PCM1 PHF5A PPIE QKI RAF1 RBM22 RBPMS RNF10 RPL36AL RYBP SF3B4 SMARCA2 SNRNP200 SNRNP48 SNRNP70 SNRPA SNRPF SRRM2 SRSF2 SRSF8 SUMO2 SUN2 TFIP11 THOC1 TIMM44 TRAK1 TRMT1L TSNAXIP1 TXNL4B USO1 VIM YWHAB ZRSR2
Entrez ID		64963	24148
HPRD ID		14776	10729
Ensembl ID		ENSG00000181991	ENSG00000101161
Uniprot IDs		P82912	O94906
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 8H6E 8H6J 8H6K 8H6L 8Q7N 8Q7Q 8Q7V 8Q7W 8Q7X 8Q91 8QO9 8QOZ 8QP8 8QP9 8QPA 8QPB 8QPE 8QPK 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RC0 8RM5 8Y6O
Enriched GO Terms of Interacting Partners?		Spliceosomal Complex Assembly Protein-N-terminal-alanine Acetyltransferase Activity Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Protein N-terminal-serine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Protein-RNA Complex Assembly Regulation Of Centromeric Sister Chromatid Cohesion Negative Regulation Of Sister Chromatid Cohesion NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity Internal Protein Amino Acid Acetylation N-terminal Protein Amino Acid Acetylation RNA Splicing N-acetyltransferase Activity Nuclear Speck Sperm DNA Condensation Regulation Of Sister Chromatid Cohesion Acetyltransferase Activity Spliceosomal Tri-snRNP Complex Assembly U5 SnRNP MRNA Processing	RNA Binding MRNA Processing RNA Processing MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex RNA Metabolic Process Nucleic Acid Binding Nuclear Speck Nucleus Nucleic Acid Metabolic Process Macromolecule Metabolic Process MRNA Binding Nucleobase-containing Compound Metabolic Process U4/U6 X U5 Tri-snRNP Complex Nucleoplasm Regulation Of RNA Splicing U12-type Spliceosomal Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome Protein Binding Identical Protein Binding U2-type Catalytic Step 2 Spliceosome U5 SnRNP Ribonucleoprotein Complex Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process Estrogen Response Element Binding Regulation Of MRNA Processing Microtubule Anchoring At Microtubule Organizing Center Spliceosomal Complex Assembly U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing U1 SnRNP Estrogen Receptor Signaling Pathway Regulation Of Primary Metabolic Process Microtubule Anchoring U2-type Prespliceosome Assembly Protein-RNA Complex Assembly Nuclear Migration Regulation Of Alternative MRNA Splicing, Via Spliceosome U2 SnRNP Nuclear Matrix Steroid Binding Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process U2-type Spliceosomal Complex Steroid Hormone Receptor Signaling Pathway
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