CREBZF and ACYP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CREBZF	ACYP2
Description		CREB/ATF bZIP transcription factor	acylphosphatase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Mitochondrion RNA Polymerase II Transcription Regulator Complex	Mitochondrion
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding	Acylphosphatase Activity Protein Binding Hydrolase Activity Identical Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Response To Virus ATF6-mediated Unfolded Protein Response Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-binding Transcription Factor Activity Integrated Stress Response Signaling	Phosphate-containing Compound Metabolic Process
Pathways
Drugs			Formic acid
Diseases
GWAS		Refractive error ( 32231278)	Blood protein levels ( 30072576) Chronotype ( 27494321 30696823) Heel bone mineral density ( 30598549) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Leukocyte telomere length ( 31171785 32109421) Morning vs. evening chronotype ( 27494321) Refractive error ( 32231278) Sudden cardiac arrest ( 21658281) Telomere length ( 23535734)
Interacting Genes		19 interacting genes: ACYP2 ATF4 ATF6B BTG3 CTNNBL1 DSCR9 HCFC1 HEY1 LCOR NFE2L1 NFE2L2 NRIP1 RALBP1 RSPH1 TIAM1 TP53 TTC23 XBP1 ZNF512B	2 interacting genes: CREBZF SULT2B1
Entrez ID		58487	98
HPRD ID		07340	00028
Ensembl ID		ENSG00000137504	ENSG00000170634
Uniprot IDs		E9PIM0 Q9NS37	A0A140VJD7 E9PF46 F8WA34 P14621 U3KQL2
PDB IDs
Enriched GO Terms of Interacting Partners?		ER-nucleus Signaling Pathway Cellular Response To Glucose Starvation Response To Endoplasmic Reticulum Stress Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Response To Endoplasmic Reticulum Stress DNA-binding Transcription Factor Activity Negative Regulation Of RNA Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Transcription Cis-regulatory Region Binding Nuclear Estrogen Receptor Binding Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Regulator Complex Histone Deacetylase Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleoplasm ATF6-mediated Unfolded Protein Response Response To Oxidative Stress Cellular Response To Starvation Regulation Of Intrinsic Apoptotic Signaling Pathway RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of RNA Metabolic Process PERK-mediated Unfolded Protein Response Promoter-specific Chromatin Binding Cellular Response To Oxidative Stress General Transcription Initiation Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Response To Starvation Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Nutrient Levels DNA Binding Positive Regulation Of ERAD Pathway Cellular Response To Laminar Fluid Shear Stress DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Cellular Response To Chemical Stress Negative Regulation Of Macromolecule Biosynthetic Process Intracellular Signaling Cassette Nucleus Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Alcohol Sulfotransferase Activity Cholesterol Sulfotransferase Activity Steroid Sulfotransferase Activity 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Steroid Hormone Binding ATF6-mediated Unfolded Protein Response Sulfation Small Molecule Binding Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Epidermis Development Sulfotransferase Activity Integrated Stress Response Signaling ER-nucleus Signaling Pathway Cholesterol Binding Regulation Of Epidermis Development Positive Regulation Of Epithelial Cell Differentiation Regulation Of Epidermal Cell Differentiation Endoplasmic Reticulum Unfolded Protein Response
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