BLVRA and AGPS

Data Source: HiPPIP (Novel)

		BLVRA	AGPS
Name		biliverdin reductase A	alkylglycerone phosphate synthase
Structure			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane
	Molecular Function	Nucleotide Binding Biliverdin Reductase [NAD(P)H] Activity Protein Binding Zinc Ion Binding Oxidoreductase Activity Metal Ion Binding Biliberdin Reductase (NADH) Activity Biliverdin Reductase (NADPH) Activity	Catalytic Activity Protein Binding Alkylglycerone-phosphate Synthase Activity Transferase Activity Flavin Adenine Dinucleotide Binding FAD Binding
	Biological Process	Fatty Acid Metabolic Process Triglyceride Metabolic Process Chemotaxis Inflammatory Response Response To Oxidative Stress Gene Expression Response To Food Response To Lipopolysaccharide Lipid Oxidation Complement Component C5a Signaling Pathway Heme Catabolic Process Pigment Metabolic Process Sensory Perception Of Itch Response To Cyclosporin A	Lipid Metabolic Process Lipid Biosynthetic Process Ether Lipid Biosynthetic Process
Pathways		Heme degradation Cytoprotection by HMOX1	Plasmalogen biosynthesis Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins
Drugs		NADH	None
Diseases		None	Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)
GWAS		Mean corpuscular volume ( 32888494 ) Peak insulin response ( 28490609 )	Height ( 28552196 )
Novel Interactors		1 novel interactors: AGPS	12 novel interactors: BLVRA BOLL CHRND CS FKBP7 GORASP2 KCNH7 KEL LST1 NFIA PDE11A TSFM
Interacting Genes		5 interacting genes: AKT1 AKT2 LNX1 PRKCB PRKCZ	2 interacting genes: GNPAT GORASP1
Entrez ID		644	8540
HPRD ID		11229	04337
Ensembl ID		ENSG00000106605	ENSG00000018510
Uniprot IDs		A0A140VJF4 P53004	B7Z3Q4 O00116
PDB IDs		2H63	Not available
GO Terms Enriched among Interactors		Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Transferase Activity Regulation Of D-glucose Transmembrane Transport Protein Serine Kinase Activity Negative Regulation Of Fatty Acid Transport Regulation Of Long-chain Fatty Acid Import Into Cell Peripheral Nervous System Myelin Maintenance Cellular Response To Insulin Stimulus Protein Serine/threonine Kinase Activity Negative Regulation Of Transmembrane Transport Negative Regulation Of PERK-mediated Unfolded Protein Response Mammary Gland Epithelial Cell Differentiation Glycogen Biosynthetic Process Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Fatty Acid Beta-oxidation Myelin Maintenance Positive Regulation Of Glycogen Biosynthetic Process Protein Kinase Activity Diacylglycerol-dependent Serine/threonine Kinase Activity Response To Insulin Cell Cortex Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Peptide Hormone Stimulus Kinase Activity Protein Localization To Plasma Membrane Polysaccharide Biosynthetic Process Protein Modification Process Protein Localization To Cell Periphery Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Transport Regulation Of Fatty Acid Oxidation Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of D-glucose Import Negative Regulation Of Lipid Transport Regulation Of Glycogen Metabolic Process Cellular Response To Oxygen-containing Compound Positive Regulation Of D-glucose Transmembrane Transport Positive Regulation Of Glucose Metabolic Process Response To Peptide Hormone Protein Localization To Membrane Positive Regulation Of Translational Initiation Negative Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Response To Endoplasmic Reticulum Stress Cellular Response To Hormone Stimulus Protein Phosphorylation Regulation Of D-glucose Import Regulation Of Lipid Catabolic Process Glycogen Metabolic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration	None