BLVRA

Name	biliverdin reductase A
Structure
Novel Interactors	1 novel interactors: AGPS
Interactors	5 interactors: AKT1 AKT2 LNX1 PRKCB PRKCZ
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Nucleotide Binding Biliverdin Reductase [NAD(P)H] Activity Protein Binding Zinc Ion Binding Oxidoreductase Activity Metal Ion Binding Biliberdin Reductase (NADH) Activity Biliverdin Reductase (NADPH) Activity
	Biological Process	Fatty Acid Metabolic Process Triglyceride Metabolic Process Chemotaxis Inflammatory Response Response To Oxidative Stress Gene Expression Response To Food Response To Lipopolysaccharide Lipid Oxidation Complement Component C5a Signaling Pathway Heme Catabolic Process Pigment Metabolic Process Sensory Perception Of Itch Response To Cyclosporin A
Pathways	Heme degradation Cytoprotection by HMOX1
Drugs	NADH
GWAS	Mean corpuscular volume ( 32888494 ) Peak insulin response ( 28490609 )
Entrez ID	644
HPRD ID	11229
Ensembl ID	ENSG00000106605
Uniprot IDs	A0A140VJF4 P53004
PDB IDs	2H63
GO Terms Enriched among Interactors ?	Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Transferase Activity Regulation Of D-glucose Transmembrane Transport Protein Serine Kinase Activity Negative Regulation Of Fatty Acid Transport Regulation Of Long-chain Fatty Acid Import Into Cell Peripheral Nervous System Myelin Maintenance Cellular Response To Insulin Stimulus Protein Serine/threonine Kinase Activity Negative Regulation Of Transmembrane Transport Negative Regulation Of PERK-mediated Unfolded Protein Response Mammary Gland Epithelial Cell Differentiation Glycogen Biosynthetic Process Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Fatty Acid Beta-oxidation Myelin Maintenance Positive Regulation Of Glycogen Biosynthetic Process Protein Kinase Activity Diacylglycerol-dependent Serine/threonine Kinase Activity Response To Insulin Cell Cortex Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Peptide Hormone Stimulus Kinase Activity Protein Localization To Plasma Membrane Polysaccharide Biosynthetic Process Protein Modification Process Protein Localization To Cell Periphery Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Transport Regulation Of Fatty Acid Oxidation Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of D-glucose Import Negative Regulation Of Lipid Transport Regulation Of Glycogen Metabolic Process Cellular Response To Oxygen-containing Compound Positive Regulation Of D-glucose Transmembrane Transport Positive Regulation Of Glucose Metabolic Process Response To Peptide Hormone Protein Localization To Membrane Positive Regulation Of Translational Initiation Negative Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Response To Endoplasmic Reticulum Stress Cellular Response To Hormone Stimulus Protein Phosphorylation Regulation Of D-glucose Import Regulation Of Lipid Catabolic Process Glycogen Metabolic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration