SELL and PRKCQ

Number of citations of the paper that reports this interaction (PMID 15192100)
4

Data Source:
BioGRID (pull down)

		SELL	PRKCQ
Gene Name		selectin L	protein kinase C, theta
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Immunological Synapse Cytosol Plasma Membrane
	Molecular Function	Protease Binding Protein Binding Heparin Binding Carbohydrate Binding Glycosphingolipid Binding Cell Adhesion Molecule Binding	Protein Serine/threonine Kinase Activity Protein Kinase C Activity Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Cell Adhesion Blood Coagulation Response To ATP Regulation Of Immune Response Leukocyte Migration	Regulation Of Cell Growth Regulation Of Transcription, DNA-templated Protein Phosphorylation Membrane Protein Ectodomain Proteolysis Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Inflammatory Response Axon Guidance Blood Coagulation Phototransduction, Visible Light Rhodopsin Mediated Signaling Pathway Protein Ubiquitination Regulation Of Rhodopsin Mediated Signaling Pathway Platelet Activation Positive Regulation Of Interleukin-17 Production Positive Regulation Of Interleukin-4 Production Intracellular Signal Transduction Fc-epsilon Receptor Signaling Pathway Positive Regulation Of T Cell Proliferation Positive Regulation Of Interleukin-2 Biosynthetic Process Innate Immune Response Negative Regulation Of Insulin Receptor Signaling Pathway T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of T Cell Apoptotic Process Regulation Of Platelet Aggregation Positive Regulation Of T-helper 17 Type Immune Response Positive Regulation Of T-helper 2 Cell Activation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall Adaptive Immune System	G alpha (q) signalling events Signaling by GPCR Downstream TCR signaling Axon guidance Effects of PIP2 hydrolysis FCERI mediated NF-kB activation Inactivation, recovery and regulation of the phototransduction cascade Gastrin-CREB signalling pathway via PKC and MAPK The phototransduction cascade Programmed Cell Death G alpha (z) signalling events Netrin-1 signaling Innate Immune System Apoptotic cleavage of cellular proteins Apoptotic execution phase Diseases associated with visual transduction G alpha (q) signalling events GPCR downstream signaling TCR signaling Visual phototransduction Fc epsilon receptor (FCERI) signaling Platelet activation, signaling and aggregation Adaptive Immune System
Drugs			Staurosporine Phosphonothreonine Phosphonoserine
Diseases
GWAS		Amyotrophic lateral sclerosis ( 19451621)	Asthma (bronchodilator response) ( 23508266) Body mass index (asthmatics) ( 23517042) Immune response to smallpox vaccine (IL-6) ( 22542470) Rheumatoid arthritis ( 18794853 20453842) Type 1 diabetes ( 19430480 18978792)
Protein-Protein Interactions		15 interactors: CD4 CFH EMCN EZR GRB2 MSN MUC7 PODXL PODXL2 PRKCA PRKCQ PRKG1 SELE SELPLG VCAN	28 interactors: AKT1 BTK CARD11 CASP3 CBL CHUK CISH FYN GLRX3 GRM5 HABP4 ICAM3 IKBKB IKBKG IRS1 LCK LYN MARK3 MSN NFE2L2 RASGRP3 SELL STK39 TAL1 VAV1 WIPF1 YWHAG YWHAQ
Entrez ID		6402	5588
HPRD ID		07034	02710
Ensembl ID		ENSG00000188404	ENSG00000065675
Uniprot IDs		P14151	Q04759
PDB IDs		1KJB 2LGF 3CFW	1XJD 2ENJ 2ENN 2ENZ 2JED
Enriched GO Terms of Interacting Partners?		Locomotion Movement Of Cell Or Subcellular Component Leukocyte Migration Cell Migration Cell Motility Cell Adhesion Leukocyte Cell-cell Adhesion Immune System Process Regulation Of Cell-cell Adhesion Leukocyte Tethering Or Rolling Blood Coagulation Hemostasis Regulation Of Platelet Aggregation Single Organismal Cell-cell Adhesion Regulation Of Body Fluid Levels Cellular Extravasation Wound Healing Regulation Of Platelet Activation Regulation Of Cell Adhesion Response To Wounding Positive Regulation Of Cell Adhesion Membrane To Membrane Docking Regulation Of Immune System Process Regulation Of Cell Activation Positive Regulation Of Immune System Process Positive Regulation Of Cell-cell Adhesion Cell Differentiation Regulation Of Blood Coagulation Cell Activation Positive Regulation Of Interleukin-2 Biosynthetic Process Regulation Of Wound Healing Defense Response Innate Immune Response Cellular Response To Radiation Regulation Of Interleukin-2 Biosynthetic Process Regulation Of Rhodopsin Mediated Signaling Pathway Establishment Of Endothelial Barrier Rhodopsin Mediated Signaling Pathway Platelet Activation Positive Regulation Of Interleukin-2 Production Positive Regulation Of T Cell Activation Epithelial Cell Development Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Response To Stress Receptor Internalization Regulation Of Cell Migration Chemotaxis Cell Development Response To External Stimulus	Fc Receptor Signaling Pathway Fc-epsilon Receptor Signaling Pathway Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Immune Response Immune Response-activating Cell Surface Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Intracellular Signal Transduction Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Neurotrophin Signaling Pathway Regulation Of Apoptotic Process Immune System Process T Cell Costimulation Regulation Of Cell Death Positive Regulation Of Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Immune Response Regulation Of Intracellular Signal Transduction Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor T Cell Receptor Signaling Pathway Signal Transduction Regulation Of Signaling Immune Response Regulation Of Lymphocyte Activation Cellular Response To Growth Factor Stimulus Phosphatidylinositol-mediated Signaling Defense Response Lymphocyte Homeostasis Signaling Response To Growth Factor Cell Communication Response To Organic Substance Response To Stress Cellular Response To Stimulus Regulation Of T Cell Activation Leukocyte Homeostasis Phosphorylation Positive Regulation Of Cell Activation Regulation Of Cell Activation Cell Surface Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus
Tagcloud ?		aw cereal cereals consignments contents corrected damaged dry heterogeneity ill infestation insects inspection kernels mould overseas portion prompt safe shipments shipped storage substance substantiated substituted theoretical trade usefully validity	aurkb bub1b ccnb1 cd247 cd3d cd3g cd8a cdc20 cdca8 cenpa cytoscape dihydroxyfluorane epstain generank hindering itgb5 itk kif2c lcp2 limma lymphoblasts mad2l1 nup37 pik3r3 plcg2 rpa3 softwares vav3 zap70
Tagcloud (Difference) ?		aw cereal cereals consignments contents corrected damaged dry heterogeneity ill infestation insects inspection kernels mould overseas portion prompt safe shipments shipped storage substance substantiated substituted theoretical trade usefully validity	aurkb bub1b ccnb1 cd247 cd3d cd3g cd8a cdc20 cdca8 cenpa cytoscape dihydroxyfluorane epstain generank hindering itgb5 itk kif2c lcp2 limma lymphoblasts mad2l1 nup37 pik3r3 plcg2 rpa3 softwares vav3 zap70
Tagcloud (Intersection) ?